Evolutionary trajectory and characteristics of Mpox virus in 2023 based on a large-scale genomic surveillance in Shenzhen, China

• Published in: Nature communications Vol. 15; no. 1; pp. 7452 - 11
• Main Authors: Zhang, Shengjie, Wang, Fuxiang, Peng, Yun, Gong, Xiaohua, Fan, Guohao, Lin, Yuanlong, Yang, Liuqing, Shen, Liang, Niu, Shiyu, Liu, Jiexiang, Yin, Yue, Yuan, Jing, Lu, Hongzhou, Liu, Yingxia, Yang, Yang
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 28.08.2024; Nature Publishing Group; Nature Portfolio
• Subjects: 45; 45/23; 631/181/735; 631/208/212/2304; 631/326/421; 692/700/478/174; Amino acids; APOBEC Deaminases - genetics; Apolipoprotein B; China - epidemiology; Cytidine Deaminase - genetics; Disease Outbreaks; Epidemiology; Evolution; Evolution, Molecular; Gene sequencing; Genome, Viral - genetics; Genomics; Genomics - methods; Humanities and Social Sciences; Humans; Missense mutation; Monkeypox virus - genetics; Mpox; Mpox (monkeypox); mRNA; multidisciplinary; Mutation; Outbreaks; Phylogenetics; Phylogeny; Polypeptides; RNA editing; Science; Science (multidisciplinary); Trajectory analysis; Viral diseases; Viruses; China; Shenzhen China

The global epidemic of Mpox virus (MPXV) continues, and a local outbreak has occurred in Shenzhen city since June 2023. Herein, the evolutionary trajectory and characteristics of MPXV in 2023 were analyzed using 92 MPXV sequences from the Shenzhen outbreak and the available genomes from GISAID and G...