Molecular analyses of ADAMTS-1, -4, -5, and IL-17 a cytokine relationship in patients with ulcerative colitis

• Published in: BMC gastroenterology Vol. 23; no. 1; pp. 1 - 345
• Main Authors: Buran, Tahir, Batır, Muhammet Burak, Çam, Fethi Sırrı, Kasap, Elmas, Çöllü, Fatih, Çelebi, Hamide Betül Gerik, Şahin, Mustafa
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 05.10.2023; BioMed Central; BMC
• Subjects: ADAM protein; ADAMTS; ADAMTS-1 protein; Age; Analysis; Antibodies; Arthritis; Autoimmune diseases; Biological products; Chronic illnesses; Colon; Colonoscopy; Cytokines; Development and progression; Disease; Disease susceptibility; Enzyme-linked immunosorbent assay; Enzymes; Extracellular matrix; Gastroenterology; Gene expression; Genes; Helper cells; IL-17A; Immune response; Inflammation; Inflammatory bowel disease; Inflammatory bowel diseases; Interleukin 17; Interleukins; Intestine; Localization; Lymphocytes T; Pathogenesis; Proteoglycans; RNA; Serum levels; Software; Thrombospondin; Ulcerative colitis; Germany

Abstract Background Ulcerative colitis (UC) is a chronic inflammatory bowel disease that develops due to the impaired immune response in genetically susceptible individuals, and its etiopathogenesis is not fully elucidated. IL-17 A is a cytokine that is produced by a type of immune cell called Th17...