Prolonged infusion of bivalirudin after elective percutaneous coronary intervention protects against procedural myocardial injury (a COBER study)—a randomized trial

• Published in: Scientific reports Vol. 13; no. 1; pp. 6667 - 9
• Main Authors: Wu, Zhiming, Meng, Peina, Guo, Yajie, You, Wei, Wu, Xiangqi, Ye, Fei
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 24.04.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 692/4019; 692/4019/2776; Angioplasty; Anticoagulants; Bleeding; Heart; Hemorrhage - etiology; Hirudins; Humanities and Social Sciences; Humans; multidisciplinary; Myocardial Infarction - etiology; Peptide Fragments - adverse effects; Percutaneous Coronary Intervention - adverse effects; Science; Science (multidisciplinary); Treatment Outcome; Troponin I

Procedural myocardial injury (PMI), which is the most common complication of elective percutaneous coronary intervention (ePCI), is associated with future adverse cardiac events. In this randomized pilot trial, we assessed the effects of prolonged use of the anti-coagulant bivalirudin on PMI after e...