Dual-sized hollow particle incorporated fibroin thermal insulating coatings on catheter for cerebral therapeutic hypothermia

• Published in: Bioactive materials Vol. 26; pp. 116 - 127
• Main Authors: Li, Ming, Gao, Yuan, Jiang, Miaowen, Zhang, Hongkang, Zhang, Yang, Wu, Yan, Zhou, Wenhao, Wu, Di, Wu, Chuanjie, Wu, Longfei, Bao, Luzi, Ge, Xiaoxiao, Qi, Zhengfei, Wei, Ming, Li, Ang, Ding, Yuchuan, Zhang, Jicheng, Pan, Guangzhen, Wu, Yu, Cheng, Yan, Zheng, Yufeng, Ji, Xunming
• Format: Journal Article
• Language: English
• Published: China Elsevier B.V 01.08.2023; KeAi Publishing; KeAi Communications Co., Ltd
• Subjects: Catheter; Hypothermia; Silk fibroin; Stroke; Thermal insulation coating; Catheter; Silk fibroin; Stroke; Thermal insulation coating; Hypothermia

Selective endovascular hypothermia has been used to provide cooling-induced cerebral neuroprotection, but current catheters do not support thermally-insulated transfer of cold infusate, which results in an increased exit temperature, causes hemodilution, and limits its cooling efficiency. Herein, ai...