Extrusion of the medial meniscus under a weight-loading condition in early knee osteoarthritis: an investigation using special upright magnetic resonance imaging

• Published in: BMC musculoskeletal disorders Vol. 24; no. 1; pp. 1 - 680
• Main Authors: Shimozaki, Kengo, Nakase, Junsuke, Kanayama, Tomoyuki, Yanatori, Yusuke, Ishida, Yoshihiro, Ohno, Naoki, Miyati, Tosiaki, Tsuchiya, Hiroyuki
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 26.08.2023; BioMed Central; BMC
• Subjects: Analysis; Arthritis; Body piercing; Care and treatment; Development and progression; Early knee osteoarthritis; Extrusion; Knee; Magnetic resonance imaging; Medial meniscus; Medical examination; Meniscus; Meniscus (Anatomy); Morphology; Musculoskeletal diseases; Orthopedics; Osteoarthritis; Weight-loading condition; Japan
• DOI: 10.1186/s12891-023-06807-x
• ISSN: 1471-2474

Abstract Background Whether the medial meniscus morphology and movement occur under upright loading conditions in early knee osteoarthritis (OA) or medial meniscus posterior root tear (MMPRT) remains unknown. This study aimed to evaluate the medial and anteroposterior extrusion of the medial meniscus under unloaded and upright-loaded conditions in patients with early knee OA. Methods Twelve patients with early knee OA and 18 healthy adult volunteers participated in this study. Magnetic resonance imaging using special equipment was performed with the participants in the unloaded and upright-loaded conditions. Medial, anterior, and posterior extrusions of the medial meniscus against the tibial edge were evaluated and compared between the early knee OA and healthy adult control groups. Additionally, 12 patients in the early knee OA group were divided into 2 subgroups based on whether MMPRT was observed, and the extrusion of the medial meniscus was compared. Results The amount of medial extrusion of the medial meniscus in both the unloaded and upright-loaded conditions was significantly greater in the early knee OA group than in the control group (unloaded: 2.6 ± 1.0 mm vs 0.7 ± 0.5 mm; upright-loaded: 3.7 ± 0.9 mm vs 1.8 ± 0.8 mm). Similarly, the anterior and posterior extrusion of the medial meniscus in the upright-loaded condition was significantly larger in the early knee OA group (anterior: 4.6 ± 1.0 mm vs 3.7 ± 1.1 mm; posterior: -3.4 ± 1.1 mm vs -4.6 ± 1.6 mm). However, no difference was observed in meniscal extrusion between unloaded and upright-loaded conditions. The posterior extrusion of the medial meniscus in the upright-loaded condition was significantly greater in MMPRT cases than in non-MMPRT cases in the early knee OA group (MMPRT: -2.7 ± 1.1 mm; non-MMPRT -4.1 ± 1.5 mm). Conclusions In early knee OA, significantly large meniscal extrusions of the medial meniscus in both unloaded and upright-loaded conditions were found compared with healthy adults. Among patients with early knee OA, those with MMPRT showed a large posterior extrusion of the medial meniscus in the upright-loaded condition compared with those without MMPRT. Level of evidence Level IV.