Functional topography of the human entorhinal cortex

• Published in: eLife Vol. 4
• Main Authors: Navarro Schröder, Tobias, Haak, Koen V, Zaragoza Jimenez, Nestor I, Beckmann, Christian F, Doeller, Christian F
• Format: Journal Article
• Language: English
• Published: England eLife Sciences Publications Ltd 08.06.2015; eLife Sciences Publications, Ltd
• Subjects: Adult; Algorithms; Alzheimer's disease; Animals; Cognition - physiology; Connectome; Cortex (entorhinal); Data processing; entorhinal cortex; Entorhinal Cortex - anatomy & histology; Entorhinal Cortex - physiology; Experiments; Female; fMRI; Functional magnetic resonance imaging; Humans; Linear Models; Magnetic Resonance Imaging - methods; Male; medial temporal lobe; Mice; Models, Neurological; Navigation behavior; Neuroimaging; Neuroscience; NMR; Nuclear magnetic resonance; Spatial memory; Spatial Navigation - physiology; Standard deviation; fMRI; entorhinal cortex; medial temporal lobe; human; neuroscience

Despite extensive research on the role of the rodent medial and lateral entorhinal cortex (MEC/LEC) in spatial navigation, memory and related disease, their human homologues remain elusive. Here, we combine high-field functional magnetic resonance imaging at 7 T with novel data-driven and model-base...