Indoor-air purification by photoelectrochemical oxidation mitigates allergic airway responses to aerosolized cat dander in a murine model

• Published in: Scientific reports Vol. 13; no. 1; p. 10980
• Main Authors: Devadoss, Dinesh, Surbaugh, Kerri, Manevski, Marko, Wickramaratne, Chatura, Chaput, Dale, Chung, Arianne, de Leon, Francisco, Chand, Hitendra S., Dhau, Jaspreet S.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 06.07.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 631/250; 631/45; 639/166; 639/301; 639/638; 704/172; Air purification; Air quality; Allergens; Allergies; Animal models; Asthma; Dander; Eosinophilia; Filtration; Humanities and Social Sciences; Hyperplasia; Indoor air quality; Indoor environments; Interleukin 13; multidisciplinary; Peptides; Proteomics; Respiratory tract; Science; Science (multidisciplinary)

Portable air purifiers help improve indoor air quality by neutralizing allergens, including animal dander proteins. However, there are limited in-vivo models to assess the efficacy of these devices. Here, we developed a novel animal model of experimental asthma using aerosolized cat dander extract (...