Decreased inhibin B responses following recombinant human chorionic gonadotropin administration in normal women and women with polycystic ovary syndrome

• Published in: Fertility and sterility Vol. 101; no. 1; pp. 275 - 279
• Main Authors: Shayya, Rana F., Rosencrantz, Marcus A., Chuan, Sandy S., Cook-Andersen, Heidi, Roudebush, William E., Irene Su, H., Shimasaki, Shunichi, Chang, R. Jeffrey
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.01.2014
• Subjects: Adult; Biomarkers - blood; Chorionic Gonadotropin - therapeutic use; Female; hCG; Humans; Inhibin B; Inhibins - blood; Internal Medicine; Obstetrics and Gynecology; polycystic ovary syndrome; Polycystic Ovary Syndrome - blood; Polycystic Ovary Syndrome - drug therapy; Prospective Studies; Recombinant Proteins - therapeutic use; Treatment Outcome; hCG; Inhibin B; polycystic ovary syndrome

To determine whether granulosa cells contribute to excess androgen production, by assessing inhibin B (Inh B) responses to hCG in women with polycystic ovary syndrome (PCOS) and in normal women. Prospective study. Academic medical center. Twenty women with PCOS and 16 normal women. Blood samples obt...