Sustained bloodstream release of persistent organic pollutants induced by extensive weight loss after bariatric surgery: Implications for women of childbearing age

• Published in: Environment international Vol. 151; no. 1; p. 106400
• Main Authors: Fénichel, Patrick, Coquillard, Patrick, Brucker-Davis, Françoise, Marchand, Philippe, Cano-Sancho, German, Boda, Mireille, Antignac, Jean-Philippe, Iannelli, Antonio, Gugenheim, Jean, Le Bizec, Bruno, Chevalier, Nicolas
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.06.2021; Elsevier
• Subjects: Adult; Bariatric Surgery; blood flow; blood serum; breast feeding; bromination; chlorination; Critical exposure values; DDE (pesticide); Endocrine disruptors; environment; Environment and Society; Environmental Pollutants - analysis; Environmental Sciences; Female; fetus; gender; hexachlorobenzene; Humans; Hydrocarbons, Chlorinated - analysis; lipophilicity; Male; metabolic syndrome; metabolites; Morbid obesity; Obesity, Morbid - surgery; Persistent Organic Pollutants; Pesticides - analysis; Polychlorinated Biphenyls - analysis; Weight Loss; Women of childbearing age; Endocrine disruptors; ΣPCB; ADI; Bariatric surgery; DL; EDI; lw; p,p′-DDE; NDL-PCB; PFAS; BFR; EDCs; PeCBz; PBB; SD; BW; DDT; PBDE; Persistent organic pollutants; BMI; LOD; WCBA; HCB; Women of childbearing age; PFOA; LOQ; POP; Critical exposure values; β-HCH; Morbid obesity; OCP; PFOS

•One year after surgery, serum POPs levels increased up to 35 to 130%.•Increases depended on weight loss, gender and POP’s lipophilicity.•After one year, ∑PCB6 exceeded critical threshold in 25% women of childbearing age versus 3.6% before.•Fetal and infant health risks should be considered for reco...