Targeting intestinal flora and its metabolism to explore the laxative effects of rhubarb - Yang, Lei; Wan, Yue; Li, Wenwen; Liu, Chen; Li, Hui-fang; Dong, Zhiling; Zhu, Ke; Jiang, Shu; Shang, Erxin; Qian, Dawei; Duan, Jinao (Applied microbiology and biotechnology, 2022)
Keywords: 25-hydroxycholecalciferol; Acids; Animals; Applied Microbial and Cell Physiology; Biomedical and Life Sciences; Biotechnology; Chenodeoxycholic acid; Cholic acid; Colon; Constipation; Correlation analysis; Defecation; Digestive system; Drugs, Chinese Herbal - pharmacology; Drugs, Chinese Herbal - therapeutic use; Feces; Feces - microbiology; Gastrointestinal Microbiome; Gastrointestinal tract; gastrointestinal transit; Gene sequencing; genes; Health aspects; Herbal medicine; High performance liquid chromatography; Intestinal microflora; intestinal microorganisms; Intestine; Laxatives; Laxatives - analysis; Laxatives - pharmacology; Laxatives - therapeutic use; Life Sciences; Linolenic acid; Liquid chromatography; lithocholic acid; Mass spectrometry; Mass spectroscopy; Metabolism; Metabolites; metabolome; Metabolomics; metagenomics; Microbial Genetics and Genomics; Microbiology; Microbiota; Microbiota (Symbiotic organisms); Moisture content; mucus; Next-generation sequencing; Physiological aspects; Probiotics; prostaglandins; Quadrupoles; Rats; Rheum - chemistry; Rhubarb; RNA, Ribosomal, 16S - genetics; rRNA 16S; Testing; Transit time; Water content; China; Gut microbiota; Rhubarb; Metabolites; Constipation