A single nucleotide polymorphism in dopamine beta hydroxylase (rs6271(C>T)) is over-represented in inflammatory bowel disease patients and reduces circulating enzyme - Gonzalez-Lopez, Eugene; Kawasawa-Imamura, Yuka; Zhang, Lijun; Huang, Xuemei; Koltun, Walter A.; Coates, Matthew D.; Vrana, Kent E. (PloS one, 2019)
Keywords: Amino Acid Substitution; Biology and Life Sciences; Blood flow; Cardiotonic agents; Dopamine; Dopamine beta-Hydroxylase - blood; Dopamine beta-Hydroxylase - genetics; Enzyme-linked immunosorbent assay; Enzymes; Exome; Exome sequencing; Female; Gastrointestinal diseases; Gastrointestinal system; Genetic aspects; Genetic polymorphisms; Humans; Hydroxylases; Inflammatory bowel diseases; Inflammatory Bowel Diseases - enzymology; Inflammatory Bowel Diseases - genetics; Male; Medicine and Health Sciences; Neurons; Phenols (Class of compounds); Physical Sciences; Polymorphism, Single Nucleotide; Research and Analysis Methods; Risk factors; Single nucleotide polymorphisms; Germany