PKM2 aggregation drives metabolism reprograming during aging process - Bie, Juntao; Li, Ridong; Li, Yutong; Song, Chen; Chen, Zhaoming; Zhang, Tianzhuo; Tang, Zhiheng; Su, Li; Zhu, Liangyi; Wang, Jiaxin; Wan, You; Chen, Jun; et al. (Nature communications, 2024)
Keywords: 13/31; 14/19; 14/35; 38/91; 631/154/555; 631/80/470/2284; 631/80/509; 64/60; 82/80; Age related diseases; Aggregates; Aging; Aging - metabolism; Animals; Carrier Proteins - metabolism; Cellular Senescence; Driving ability; Enzymatic activity; Glycolysis; Humanities and Social Sciences; Humans; Life span; Male; Membrane Proteins - genetics; Membrane Proteins - metabolism; Mice; Mice, Inbred C57BL; multidisciplinary; Phenotypes; Protein Aggregates; Protein interaction; Protein turnover; Proteins; Pyruvate Kinase - metabolism; Science; Science (multidisciplinary); Senescence; Thyroid Hormone-Binding Proteins; Thyroid Hormones - metabolism