Identification of tophi in ultrasound imaging based on transfer learning and clinical practice

• Published in: Scientific reports Vol. 13; no. 1; pp. 12507 - 7
• Main Authors: Lin, Tzu-Min, Lee, Hsiang-Yen, Chang, Ching-Kuei, Lin, Ke-Hung, Chang, Chi-Ching, Wu, Bing-Fei, Peng, Syu-Jyun
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 02.08.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 631/250; 692/4023; Arthritis; Arthritis, Gouty; Computed tomography; Crystals; Gout; Gout - diagnostic imaging; Humanities and Social Sciences; Humans; Inflammation; Machine Learning; Metabolic disorders; multidisciplinary; Neural networks; Reproducibility of Results; Rheumatism; Science; Science (multidisciplinary); Tomography; Tomography, X-Ray Computed - methods; Transfer learning; Ultrasonic imaging; Ultrasonography - methods; Ultrasound; Uric acid; Uric Acid - metabolism

Gout is a common metabolic disorder characterized by deposits of monosodium urate monohydrate crystals (tophi) in soft tissue, triggering intense and acute arthritis with intolerable pain as well as articular and periarticular inflammation. Tophi can also promote chronic inflammatory and erosive art...