Serum Levels of Uric Acid and Diabetes Mellitus Influence Survival after Surgery for Primary Hyperparathyroidism: A Prospective Cohort Study

• Published in: World journal of surgery Vol. 31; no. 7; pp. 1393 - 1400
• Main Authors: Bergenfelz, Anders, Bladström, Anna, Their, Mark, Nordenström, Erik, Valdemarsson, Stig, Westerdahl, Johan
• Format: Journal Article
• Language: English
• Published: New York Springer‐Verlag 01.07.2007; Springer; Springer Nature B.V
• Subjects: Adenoma - complications; Adolescent; Adult; Aged; Aged, 80 and over; Biological and medical sciences; Calcium - blood; Clinical Medicine; Creatinine - blood; Diabetes Mellitus - epidemiology; Diabetes. Impaired glucose tolerance; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Female; General aspects; Glomerular Filtration Rate; Humans; Hyperparathyroidism, Primary - blood; Hyperparathyroidism, Primary - epidemiology; Hyperparathyroidism, Primary - etiology; Hyperparathyroidism, Primary - mortality; Hyperparathyroidism, Primary - surgery; Kirurgi; Klinisk medicin; Male; Medical and Health Sciences; Medical sciences; Medicin och hälsovetenskap; Middle Aged; Parathyroid Neoplasms - complications; Primary Hyperparathyroidism; Proportional Hazards Models; Prospective Studies; Serum Uric Acid; Surgery; Survival Analysis; Triglycerides - blood; Uric Acid; Uric Acid - blood; Uric Acid Level; Endocrinopathy; Diabetes mellitus; Uric acid; Survival; Medicine; Prospective; Treatment; Parathyroid diseases; Surgery; Cohort study; Primary; Serum; Hyperparathyroidism; Public health

Background Primary hyperparathyroidism (pHPT) is associated with an increased mortality attributable to cardiovascular disease (CVD), suggested to be alleviated by surgery. The exact mechanism of the beneficial influence of parathyroidectomy on survival is unknown. Furthermore, studies suggest that...