Th40 cells (CD4+CD40+ Tcells) drive a more severe form of Experimental Autoimmune Encephalomyelitis than conventional CD4 T cells - Vaitaitis, Gisela M.; Yussman, Martin G.; Waid, Dan M.; Wagner, David H. (PloS one, 2017)
Keywords: Adoptive Transfer; Animals; Antigens; Autoimmune diseases; Biology and Life Sciences; Blotting, Western; Brain - immunology; Brain - metabolism; Care and treatment; CD4 antigen; CD4-Positive T-Lymphocytes - immunology; CD4-Positive T-Lymphocytes - metabolism; CD40 antigen; CD40 Antigens - immunology; CD40 Antigens - metabolism; CD40L protein; Cell Movement - immunology; Cell Proliferation; Central nervous system; Central Nervous System - immunology; Central Nervous System - metabolism; Coinjection; Complications and side effects; Cytokines - immunology; Cytokines - metabolism; Demyelinating Diseases - immunology; Demyelinating Diseases - metabolism; Demyelination; Diabetes; Diabetes mellitus; Encephalomyelitis; Encephalomyelitis, Autoimmune, Experimental - immunology; Encephalomyelitis, Autoimmune, Experimental - metabolism; Experimental allergic encephalomyelitis; Female; Flow Cytometry; Freund's Adjuvant - immunology; Genetic aspects; Haplotypes; Health aspects; Honing; Human subjects; Immunoglobulins; Immunology; Infiltration; Interferon-gamma - immunology; Interferon-gamma - metabolism; Laboratory animals; Lesions; Lymphocytes; Lymphocytes T; Medicine; Medicine and Health Sciences; Mice, Inbred C57BL; Mice, SCID; Multiple sclerosis; Myelin-Oligodendrocyte Glycoprotein - immunology; Nervous system; Oligodendrocyte-myelin glycoprotein; Peptide Fragments - immunology; Research and Analysis Methods; Spinal Cord - immunology; Spinal Cord - metabolism; T cell receptors; T cells; T-cell receptor; Trauma; Canada