Spontaneous regression of tumor in a girl with optic pathway glioma with diencephalic syndrome

• Published in: Pediatric investigation Vol. 7; no. 1; pp. 60 - 62
• Main Authors: Luo, Rutao, Zhang, Tianlei, Yang, Wei, Ji, Yuanqi, Sun, Hailang, Li, Dapeng, Ge, Ming
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.03.2023; John Wiley and Sons Inc; Wiley
• Subjects: Age; Cysts; Letter to the Editor; Magnetic resonance imaging; Medical prognosis; Patients; Tumors
• ISSN: 2574-2272; 2096-3726; 2574-2272
• DOI: 10.1002/ped4.12356

Magnetic resonance imaging (MRI) demonstrated a 42 mm × 37 mm × 36 mm enhanced and lobulated lesion with a large cystic component at the bottom located in the sellar region with a clear boundary with surrounding tissues (Figure 1A, B). Some can remain stable for a long time but some grow or spread rapidly, and several even shrink or disappear naturally. 1–3 Optic pathway gliomas also lead to various endocrine changes, including DS. 4 Diencephalic syndrome can lead to difficulty in gain weight in pediatric patients, usually secondary to neoplastic lesions nearby hypothalamus, was closely related to the OPGs. 5 Some studies have shown that OPG patients with DS have a poor prognosis. [...]some studies had shown tissue regression of astrocytoma located in several positions. 10 Some believed reduced proliferation could be secondary to enhanced immunocompetence and immune recognition of tumors. 9 Treatment for OPG patients with DS is still controversial.