Recurrent infection triggered encephalopathy syndrome in a pediatric patient with RANBP2 mutation and severe acute respiratory syndrome coronavirus 2 infection

• Published in: Pediatric investigation Vol. 7; no. 4; pp. 290 - 296
• Main Authors: Li, Jiaqi, Huo, Feng, Wang, Shuo, Fan, Yimu, Wu, Jie, Zhang, Zhezhe, Liu, Shuangjun, Wang, Quan
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.12.2023; John Wiley and Sons Inc; Wiley
• Subjects: Acute necrotizing encephalopathy; Case Report; Case reports; COVID-19; Infections; Magnetic resonance imaging; Mortality; Mutation; Pediatrics; RANBP2; SARS‐CoV‐2; RANBP2; COVID‐19; Acute necrotizing encephalopathy; SARS‐CoV‐2

ABSTRACT Introduction Acute necrotizing encephalopathy (ANE), a fatal subtype of infection‐triggered encephalopathy syndrome (ITES), can be triggered by many systemic infections. RANBP2 gene mutations were associated with recurrent ANE. Case presentation Here we report a 1‐year‐old girl with recurre...