CXCL12/CXCR4 axis as a key mediator in atrial fibrillation via bioinformatics analysis and functional identification - Liu, Peng; Sun, Hongke; Zhou, Xin; Wang, Qiaozhu; Gao, Feng; Fu, Yuping; Li, Tong; Wang, Yixin; Li, Yingqi; Fan, Boyuan; Li, Xiaoli; Jiang, Tiannan; et al. (Cell death & disease, 2021)
Keywords: 13/1; 13/21; 13/51; 45/61; 45/77; 631/250/98; 631/337; 631/61/191/2018; 64; 64/60; 692/699/75/29/1309; 82/29; 82/80; Acetylcholine; AKT protein; Animal models; Animals; Antibodies; Arrhythmia; Atrial Fibrillation - diagnostic imaging; Atrial Fibrillation - genetics; Atrial Fibrillation - metabolism; Atrial Fibrillation - physiopathology; Benzylamines - administration & dosage; Benzylamines - pharmacology; Biochemistry; Bioinformatics; Biomedical and Life Sciences; Calcium chloride; Cardiac arrhythmia; Case-Control Studies; CD3 antigen; Cell Biology; Cell Culture; Chemokine CXCL12 - metabolism; Chemokines; Computational Biology; CXCL12 protein; CXCR4 protein; Cyclams - administration & dosage; Cyclams - pharmacology; Databases, Genetic; Disease Models, Animal; DNA microarrays; Electrocardiography; Extracellular matrix; Fibrillation; Fibrosis; Gene Expression Profiling; Gene Ontology; Gene Regulatory Networks; Heart Atria - drug effects; Heart Atria - pathology; Heart Atria - physiopathology; Humans; Immunology; Inflammation; Inflammation - pathology; Leukocyte migration; Life Sciences; Lymphocytes T; Macrophages; Macrophages - drug effects; Macrophages - pathology; Mice; Mice, Inbred C57BL; Phosphorylation - drug effects; Receptors, CXCR4 - metabolism; Signal transduction; Signal Transduction - drug effects; T-Lymphocytes - drug effects; T-Lymphocytes - immunology; TOR protein; Transcription; Vascular Remodeling - drug effects