Key bacterial taxa and metabolic pathways affecting gut short-chain fatty acid profiles in early life

• Published in: The ISME Journal Vol. 15; no. 9; pp. 2574 - 2590
• Main Authors: Tsukuda, Naoki, Yahagi, Kana, Hara, Taeko, Watanabe, Yohei, Matsumoto, Hoshitaka, Mori, Hiroshi, Higashi, Koichi, Tsuji, Hirokazu, Matsumoto, Satoshi, Kurokawa, Ken, Matsuki, Takahiro
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.09.2021; Oxford University Press
• Subjects: 38; 38/23; 38/91; 45; 45/77; 631/326/2565/2134; 631/326/2565/855; 631/326/325/2482; Acetic acid; Biomedical and Life Sciences; Breast feeding; Breast milk; Breastfeeding & lactation; Clostridiales; Ecology; Evolutionary Biology; Fatty acids; Fucose; Infants; Intestinal microflora; Lactic acid; Life Sciences; Metabolic pathways; Metabolites; Microbial Ecology; Microbial Genetics and Genomics; Microbiology; Microbiota; Oligosaccharides; Propionic acid; Substrates; Syntrophism

Infant gut microbiota development affects the host physiology throughout life, and short-chain fatty acids (SCFAs) are promising key metabolites mediating microbiota-host relationships. Here, we investigated dense longitudinally collected faecal samples from 12 subjects during the first 2 years ( n...