Metabolic stress induces GD2+ cancer stem cell-like phenotype in triple-negative breast cancer - Jaggupilli, Appalaraju; Ly, Stanley; Nguyen, Khoa; Anand, Vivek; Yuan, Bin; El-Dana, Fouad; Yan, Yuanqing; Arvanitis, Zoe; Piyarathna, Danthasinghe Waduge Badrajee; Putluri, Nagireddy; Piwnica-Worms, Helen; Manning, Henry Charles; et al. (British journal of cancer, 2022)
Keywords: 631/67/1347; 631/80/83; Animals; Bioinformatics; Biomedical and Life Sciences; Biomedicine; Blood Glucose - analysis; Breast cancer; Cancer Research; Cell Line, Tumor; Chemotherapy; Diabetes mellitus; Drug Resistance; Epidemiology; Female; Ferroptosis; Ferroptosis - drug effects; Flow cytometry; Gangliosides - metabolism; Genotype & phenotype; Glutamine; Glutamine - metabolism; Glutathione; Humans; Interleukin 2; Interleukin 2 receptors; Mass spectroscopy; Metabolism; Metabolomics; Metabolomics - methods; Mice; Molecular Medicine; Neoplastic Stem Cells - drug effects; Neoplastic Stem Cells - metabolism; Neoplastic Stem Cells - pathology; Nutrient deficiency; Oncology; Phenotype; Phenotypes; Severe combined immunodeficiency; Small Molecule Libraries - administration & dosage; Small Molecule Libraries - pharmacology; Stem cells; TOR protein; Triple Negative Breast Neoplasms - drug therapy; Triple Negative Breast Neoplasms - metabolism; Triple Negative Breast Neoplasms - pathology; Tumorigenesis; Tumors; Xenograft Model Antitumor Assays; Xenografts