The rs9340799 polymorphism of the estrogen receptor alpha (ESR1) gene and its association with breast cancer susceptibility

• Published in: Scientific reports Vol. 11; no. 1; pp. 18619 - 12
• Main Authors: Tan, Shing Cheng, Low, Teck Yew, Mohamad Hanif, Ezanee Azlina, Sharzehan, Mohamad Ayub Khan, Kord-Varkaneh, Hamed, Islam, Md Asiful
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 20.09.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/208; 631/67; 692/4028/67/1347; 692/4028/67/1857; 692/4028/67/68; 692/53/2421; 692/53/2423; 692/699/67/1347; Adult; Alleles; Breast cancer; Breast Neoplasms - genetics; Estrogen Receptor alpha - genetics; Estrogen receptors; Estrogens; Female; Gene polymorphism; Genetic Association Studies; Genetic markers; Genetic Predisposition to Disease; Humanities and Social Sciences; Humans; Menopause; Meta-analysis; Middle Aged; multidisciplinary; Polymorphism; Polymorphism, Single Nucleotide; Science; Science (multidisciplinary); Statistical analysis; Susceptibility

The ESR1 rs9340799 polymorphism has been frequently investigated with regard to its association with breast cancer (BC) susceptibility, but the findings have been inconclusive. In this work, we aimed to address the inconsistencies in study findings by performing a systematic review and meta-analysis...