Stuck on sugars – how carbohydrates regulate cell adhesion, recognition, and signaling

• Published in: Glycoconjugate journal Vol. 36; no. 4; pp. 241 - 257
• Main Author: Cummings, Richard D.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.08.2019; Springer Nature B.V
• Subjects: Animals; Biochemistry; Biomedical and Life Sciences; Blocking antibodies; Carbohydrates; Cell adhesion; Cell adhesion & migration; Cell Adhesion - physiology; Chaperones; Galactosyltransferases - metabolism; Glycoconjugates; Glycoconjugates - metabolism; Glycolipids; Glycomics - methods; Glycoproteins; Glycoproteins - metabolism; Glycosaminoglycans; Glycosphingolipids; Glycosylation; Humans; Immunogenicity; Inflammation - metabolism; Lectins; Lectins - metabolism; Life Sciences; Metastases; Original Article; Parasites; Pathology; Polysaccharides; Polysaccharides - metabolism; Secretions; Selectins; Signal Transduction - physiology; Sugars - metabolism; Tumorigenesis; T-synthase; Glycobiology; Glycomics; Selectins; Antibodies; Cosmc; Glycoproteins; Inflammation; Parasites; Immunity
• ISSN: 0282-0080; 1573-4986; 1573-4986
• DOI: 10.1007/s10719-019-09876-0

We have explored the fundamental biological processes by which complex carbohydrates expressed on cellular glycoproteins and glycolipids and in secretions of cells promote cell adhesion and signaling. We have also explored processes by which animal pathogens, such as viruses, bacteria, and parasites...