Histological evidence supports low anesthetic bladder capacity as a marker of a bladder-centric disease subtype in interstitial cystitis/bladder pain syndrome

• Published in: International Urogynecology Journal Vol. 30; no. 11; pp. 1863 - 1870
• Main Authors: Schachar, Jeffrey S., Evans, Robert J., Parks, Graham E., Zambon, Joao, Badlani, Gopal, Walker, Stephen J.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.11.2019; Springer Nature B.V
• Subjects: Adult; Aged; Anesthetics - pharmacology; Biomarkers; Biopsy; Bladder; Cystitis, Interstitial - classification; Cystitis, Interstitial - diagnosis; Cystitis, Interstitial - physiopathology; Female; Gene expression; Genotype & phenotype; Gynecology; Humans; Inflammation; Male; Medicine; Medicine & Public Health; Middle Aged; Original Article; Pain; Pathology; Patients; Retrospective Studies; Urinary Bladder - drug effects; Urinary Bladder - pathology; Urinary Bladder - physiopathology; Urogenital system; Urology; Histology; Bladder capacity; Subtype; Interstitial cystitis; Bladder pain syndrome

Introduction and hypothesis Low anesthetic bladder capacity has been shown to be a biomarker for bladder-centric interstitial cystitis/bladder pain syndrome (IC/BPS). The goal of this study was to determine if histopathological evidence from bladder biopsies supports anesthetic bladder capacity (BC)...