Lineage-level divergence of copepod glycerol transporters and the emergence of isoform-specific trafficking regulation

• Published in: Communications biology Vol. 4; no. 1; pp. 643 - 14
• Main Authors: Catalán-García, Marc, Chauvigné, François, Stavang, Jon Anders, Nilsen, Frank, Cerdà, Joan, Finn, Roderick Nigel
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 31.05.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 13/1; 13/51; 14/1; 14/63; 38/1; 38/22; 38/77; 42; 45; 631/181/735; 631/80/313; Alternative splicing; Animals; Aquaglyceroporins - genetics; Aquaglyceroporins - metabolism; Biological Evolution; Biology; Biomedical and Life Sciences; Conductance; Copepoda; Copepoda - genetics; Crustacea; Crustacea - genetics; Crustacea - metabolism; Divergence; Evolution; Evolution, Molecular; Evolutionary genetics; Gene duplication; Gene regulation; Genes; Genetic Variation - genetics; Glycerol; Intracellular; Kinases; Life Sciences; Membrane trafficking; Multigene Family - genetics; Mutation; Phylogeny; Protein Isoforms - genetics; Protein kinase A; Protein kinase C; Solutes; Species

Transmembrane conductance of small uncharged solutes such as glycerol typically occurs through aquaglyceroporins (Glps), which are commonly encoded by multiple genes in metazoan organisms. To date, however, little is known concerning the evolution of Glps in Crustacea or what forces might underly su...