Functional network topology of the right insula affects emotion dysregulation in hyperactive-impulsive attention-deficit/hyperactivity disorder

• Published in: Scientific reports Vol. 11; no. 1; p. 15045
• Main Authors: Viering, Tammo, Hoekstra, Pieter J., Philipsen, Alexandra, Naaijen, Jilly, Dietrich, Andrea, Hartman, Catharina A., Buitelaar, Jan K., Hildebrandt, Andrea, Gießing, Carsten, Thiel, Christiane M.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 22.07.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/378/1457; 631/378/1457/1369; 631/378/1689/2608; 631/477; 692/308; Attention Deficit Disorder with Hyperactivity - diagnosis; Attention Deficit Disorder with Hyperactivity - physiopathology; Attention deficit hyperactivity disorder; Brain; Case-Control Studies; Cerebral Cortex - physiopathology; Emotions; Humanities and Social Sciences; Humans; Hyperactivity; Image Processing, Computer-Assisted; Impulsive behavior; Impulsivity; Lability; Magnetic Resonance Imaging - methods; Models, Theoretical; multidisciplinary; Neural networks; Neural Pathways - physiopathology; Neuroimaging; Neuroimaging - methods; Science; Science (multidisciplinary); Topology; Young adults

Emotion dysregulation is common in attention-deficit/hyperactivity disorder (ADHD). It is highly prevalent in young adult ADHD and related to reduced well-being and social impairments. Neuroimaging studies reported neural activity changes in ADHD in brain regions associated with emotion processing a...