Gut microbiota, innate immune pathways, and inflammatory control mechanisms in patients with major depressive disorder

• Published in: Translational psychiatry Vol. 11; no. 1; p. 645
• Main Authors: Caso, Javier R., MacDowell, Karina S., González-Pinto, Ana, García, Saínza, de Diego-Adeliño, Javier, Carceller-Sindreu, Mar, Sarramea, Fernando, Caballero-Villarraso, Javier, Gracia-García, Patricia, De la Cámara, Concepción, Agüera, Luis, Gómez-Lus, María L., Alba, Claudio, Rodríguez, Juan M., Leza, Juan C.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 21.12.2021; Nature Publishing Group
• Subjects: 45/23; 45/29; 45/77; 692/53; 692/699/476/1414; 82/80; 96/21; Behavioral Sciences; Biological Psychology; Depressive Disorder, Major; Feces; Female; Gastrointestinal Microbiome; Humans; Immunity, Innate; Male; Medicine; Medicine & Public Health; Mental depression; Microbiota; Neurosciences; Nitric oxide; Pathophysiology; Pharmacotherapy; Psychiatry

Although alterations in the gut microbiota have been linked to the pathophysiology of major depressive disorder (MDD), including through effects on the immune response, our understanding is deficient about the straight connection patterns among microbiota and MDD in patients. Male and female MDD pat...