Cytokine and interleukin profile in patients with headache and COVID-19: A pilot, CASE-control, study on 104 patients

• Published in: Journal of headache and pain Vol. 22; no. 1; pp. 51 - 11
• Main Authors: Trigo, Javier, García-Azorín, David, Sierra-Mencía, Álvaro, Tamayo-Velasco, Álvaro, Martínez-Paz, Pedro, Tamayo, Eduardo, Guerrero, Angel Luis, Gonzalo-Benito, Hugo
• Format: Journal Article
• Language: English
• Published: Milan Springer Milan 01.12.2021; Springer Nature B.V; BMC
• Subjects: Anosmia; Case-Control Studies; Coronaviruses; COVID-19; Cytokines; Female; Fever; Headache; Headache - complications; Headache disorders; Headaches; Humans; Immune response; Immune system; Inflammation; Interleukin 1; Interleukin 1 receptor antagonist; Interleukin 10; Interleukin 21; Interleukin 22; Interleukin 23; Interleukins; Internal Medicine; Male; Medicine; Medicine & Public Health; Neurology; Olfaction disorders; Pain Medicine; Patients; Research Article; SARS-CoV-2; Statistical analysis; COVID-19; Headache disorders; Interleukins; Cytokines; Immune system

Background The presence of headache during the acute phase of COVID-19 could be associated with the innate response and the cytokine release. We aim to compare the cytokine and interleukin profile in hospitalized COVID-19 patients at the moment of admission with and without headache during the cours...