Measuring collagen injury depth for burn severity determination using polarization sensitive optical coherence tomography

• Published in: Scientific reports Vol. 12; no. 1; pp. 10479 - 11
• Main Authors: Cannon, Taylor M., Uribe-Patarroyo, Néstor, Villiger, Martin, Bouma, Brett E.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 21.06.2022; Nature Publishing Group; Nature Portfolio
• Subjects: 631/57; 639/166/985; 639/166/987; 639/624; 639/766/400; 692/308; Burns - diagnostic imaging; Burns - pathology; Collagen; Follicles; Histology; Humanities and Social Sciences; Humans; multidisciplinary; Polarization; Science; Science (multidisciplinary); Skin - pathology; Tomography; Tomography, Optical Coherence - methods; Wound Healing
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-022-14326-3

Determining the optimal treatment course for a dermatologic burn wound requires knowledge of the wound’s severity, as quantified by the depth of thermal damage. In current clinical practice, burn depth is inferred based exclusively on superficial visual assessment, a method which is subject to subst...