Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma - Cheng, Wei; Li, Hao-Long; Xi, Shao-Yan; Zhang, Xiao-Feng; Zhu, Yun; Le Xing; Mo, Yan-Xuan; Li, Mei-Mei; Kong, Fan-En; Zhu, Wen-Jie; Chen, Xiao-Gang; Cui, Hui-Qing; et al. (Nature communications, 2021)
Keywords: 13/106; 38/109; 42/89; 49/91; 59/5; 692/4028/67/1504/1610/4029; 692/4028/67/580; 692/4028/67/71; Activin; Antigens; Biomarkers; Cancer; Carcinoma, Hepatocellular - genetics; Carcinoma, Hepatocellular - metabolism; Carcinoma, Hepatocellular - pathology; Carcinoma, Hepatocellular - therapy; Cell Differentiation; Cell Line, Tumor; Cell Plasticity - drug effects; Cell Proliferation; Ectopic expression; Epigenetics; Growth differentiation factor 1; Growth Differentiation Factor 1 - metabolism; Growth Differentiation Factor 1 - pharmacology; Hepatocellular carcinoma; Homology; Humanities and Social Sciences; Humans; Immune checkpoint inhibitors; Immunogenicity; Immunotherapy; Kinases; Liver cancer; Liver Neoplasms - metabolism; Lysine; Male; Metastases; multidisciplinary; Plastic foam; Plastic properties; Plasticity; Science; Science (multidisciplinary); Signal Transduction; Signaling; Smad2 protein; Smad2 Protein - metabolism; Smad3 Protein - metabolism; Testicular Neoplasms - metabolism; Therapeutic targets; Tumors