Differential regulation of β-catenin-mediated transcription via N- and C-terminal co-factors governs identity of murine intestinal epithelial stem cells - Borrelli, Costanza; Valenta, Tomas; Handler, Kristina; Vélez, Karelia; Gurtner, Alessandra; Moro, Giulia; Lafzi, Atefeh; Roditi, Laura de Vargas; Hausmann, George; Arnold, Isabelle C.; Moor, Andreas E.; Basler, Konrad (Nature communications, 2021)
Keywords: 13/100; 38/32; 38/39; 45/100; 45/91; 631/532/2437; 631/80/86/2368; 64/60; 96/1; 96/100; 96/63; 96/95; Algorithms; Animals; Base Sequence; beta Catenin - chemistry; beta Catenin - metabolism; Cell Differentiation; Cell Proliferation; Cell self-renewal; Chromatin - metabolism; Chromatin Assembly and Disassembly; Crypts; Epithelium; Gene expression; Gene regulation; Homeostasis; Humanities and Social Sciences; Hyperplasia; Intestinal Mucosa - cytology; Intestine; JNK Mitogen-Activated Protein Kinases - metabolism; Kinases; Mice; multidisciplinary; Mutant Proteins - metabolism; Mutation; Mutation - genetics; Organoids - metabolism; Phenotype; Protein folding; RNA, Messenger - genetics; RNA, Messenger - metabolism; Science; Science (multidisciplinary); Signal Transduction; Signaling; Stem cell transplantation; Stem cells; Stem Cells - metabolism; Transcription factors; Transcription Factors - metabolism; Transcription, Genetic; Transgenic mice; Wnt protein; β-Catenin