Down but not out in posterior cingulate cortex: Deactivation yet functional coupling with prefrontal cortex during demanding semantic cognition

• Published in: NeuroImage (Orlando, Fla.) Vol. 141; pp. 366 - 377
• Main Authors: Krieger-Redwood, Katya, Jefferies, Elizabeth, Karapanagiotidis, Theodoros, Seymour, Robert, Nunes, Adonany, Ang, Jit Wei Aaron, Majernikova, Vierra, Mollo, Giovanna, Smallwood, Jonathan
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2016; Elsevier Limited; Academic Press
• Subjects: Adult; Brain Mapping - methods; Chinese languages; Cognition; Cognition & reasoning; Cognition - physiology; Connectivity; Cortex (cingulate); Deactivation; Dorsolateral prefrontal cortex; Executive; Executive function; Executive Function - physiology; Feedback, Physiological - physiology; Female; Gyrus Cinguli - physiology; Humans; Male; Memory; Mental Recall - physiology; Nerve Net - physiology; Neural Inhibition - physiology; Posterior cingulate cortex; Prefrontal cortex; Prefrontal Cortex - physiology; Rest; Semantic control; Semantics; Studies; Task Performance and Analysis; Dorsolateral prefrontal cortex; Connectivity; Rest; Semantic control; Executive; Posterior cingulate cortex

The posterior cingulate cortex (pCC) often deactivates during complex tasks, and at rest is often only weakly correlated with regions that play a general role in the control of cognition. These observations led to the hypothesis that pCC contributes to automatic aspects of memory retrieval and cogni...