Time-dependent recovery of brain hypometabolism in neuro-COVID-19 patients

• Published in: European journal of nuclear medicine and molecular imaging Vol. 50; no. 1; pp. 90 - 102
• Main Authors: Martini, Anna Lisa, Carli, Giulia, Kiferle, Lorenzo, Piersanti, Patrizia, Palumbo, Pasquale, Morbelli, Silvia, Calcagni, Maria Lucia, Perani, Daniela, Sestini, Stelvio
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.12.2022; Springer Nature B.V
• Subjects: Amygdala; Body mass index; Body size; Brain; Brain - diagnostic imaging; Brain - metabolism; Brain stem; C-reactive protein; Cardiology; Cerebellum; Cognition; Cognitive ability; Coronaviruses; Cortex (insular); COVID-19; COVID-19 - diagnostic imaging; Evaluation; Fluorodeoxyglucose F18 - metabolism; Humans; Hypometabolism; Hypoxia; Imaging; Inflammation; Inflammation - metabolism; Medicine; Medicine & Public Health; Neurological diseases; Neurology; Nuclear Medicine; Oncology; Original; Original Article; Orthopedics; Oxygen content; Patients; Positron emission tomography; Radiology; Signs and symptoms; Synergistic effect; Time dependence; Viral diseases; [; Hypermetabolism; Neuro-COVID; Hypometabolism; Recovery; F]FDG; [18F]FDG

Purpose We evaluated brain metabolic dysfunctions and associations with neurological and biological parameters in acute, subacute and chronic COVID-19 phases to provide deeper insights into the pathophysiology of the disease. Methods Twenty-six patients with neurological symptoms (neuro-COVID-19) an...