HIV-1 intron-containing RNA expression induces innate immune activation and T cell dysfunction - Akiyama, Hisashi; Miller, Caitlin M.; Ettinger, Chelsea R.; Belkina, Anna C.; Snyder-Cappione, Jennifer E.; Gummuluru, Suryaram (Nature communications, 2018)
Keywords: 13; 13/1; 13/106; 13/109; 13/21; 13/31; 13/95; 14; 14/19; 14/35; 38; 38/77; 38/88; 631/250/255/1901; 631/326/596/2553; 631/326/596/2555; 631/326/596/2557; Amino acid sequence; Antiretroviral agents; Antiretroviral drugs; Antiretroviral therapy; Cell activation; Exhaustion; Gene expression; HIV; HIV-1 - genetics; HIV-1 - immunology; Human immunodeficiency virus; Humanities and Social Sciences; Humans; Immune response; Immunity, Innate - genetics; Immunity, Innate - physiology; Inflammation; Interferon; Interferon Type I - metabolism; Introns - genetics; Lymphocytes; Lymphocytes T; Macrophages; Macrophages - metabolism; multidisciplinary; Myeloid Cells - metabolism; Nuclear transport; Nucleotide sequence; Proteins; Recovery of function; Ribonucleic acid; RNA; RNA - genetics; RNA, Viral - genetics; Science; Science (multidisciplinary); Signaling; T-Lymphocytes - metabolism; Therapy