GWAS of serum ALT and AST reveals an association of SLC30A10 Thr95Ile with hypermanganesemia symptoms - Ward, Lucas D.; Tu, Ho-Chou; Quenneville, Chelsea B.; Tsour, Shira; Flynn-Carroll, Alexander O.; Parker, Margaret M.; Deaton, Aimee M.; Haslett, Patrick A. J.; Lotta, Luca A.; Verweij, Niek; Ferreira, Manuel A. R.; Baras, Aris; et al. (Nature communications, 2021)
Keywords: 45/43; 631/208/205/2138; 692/698/2741/288/2032; 692/699/1503/1607; 692/699/67/1504/1329/1326; Alanine; Alanine transaminase; Alanine Transaminase - blood; Anemia; Aspartate aminotransferase; Aspartate Aminotransferases - blood; Bile ducts; Cation Transport Proteins - genetics; Cation Transport Proteins - metabolism; Cholangiocarcinoma; Cirrhosis; Dystonia; Enzymes; Gene Expression Regulation; Genetic diversity; Genetic Linkage; Genetic Loci; Genome, Human; Genome-wide association studies; Genome-Wide Association Study; Genomes; HeLa Cells; Hematocrit; Heterozygote; Homeostasis; Humanities and Social Sciences; Humans; Iron deficiency; Liver; Liver - pathology; Liver cirrhosis; Liver diseases; Manganese; Manganese - blood; Manganese - metabolism; Molecular Sequence Annotation; multidisciplinary; Mutation - genetics; Nutrient deficiency; Phenotype; Reproducibility of Results; Science; Science (multidisciplinary); Signs and symptoms