Regional variation in cholinergic terminal activity determines the non-uniform occurrence of cortical slow waves during REM sleep in mice

• Published in: Cell reports (Cambridge) Vol. 42; no. 5; p. 112450
• Main Authors: Nazari, Mojtaba, Karimi Abadchi, Javad, Naghizadeh, Milad, Bermudez-Contreras, Edgar J., McNaughton, Bruce L., Tatsuno, Masami, Mohajerani, Majid H.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 30.05.2023; Elsevier
• Subjects: acetylcholine; cholinergic projection; CP: Neuroscience; hippocampus; neocortex; non-rapid eye movement; NREM; rapid eye movement; REM; sleep; slow waves; wide-field mesoscale voltage and glutamate imaging; sleep; slow waves; hippocampus; CP: Neuroscience; cholinergic projection; non-rapid eye movement; NREM; neocortex; REM; acetylcholine; rapid eye movement; wide-field mesoscale voltage and glutamate imaging
• ISSN: 2211-1247; 2211-1247
• DOI: 10.1016/j.celrep.2023.112450

Sleep consists of two basic stages: non-rapid eye movement (NREM) and rapid eye movement (REM) sleep. NREM sleep is characterized by slow high-amplitude cortical electroencephalogram (EEG) signals, while REM sleep is characterized by desynchronized cortical rhythms. Despite this, recent electrophysi...