Maternal immune response and placental antibody transfer after COVID-19 vaccination across trimester and platforms

The availability of three COVID-19 vaccines in the United States provides an unprecedented opportunity to examine how vaccine platforms and timing of vaccination in pregnancy impact maternal and neonatal immunity. Here, we characterize the antibody profile after Ad26.COV2.S, mRNA-1273 or BNT162b2 va...

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Published inNature communications Vol. 13; no. 1; pp. 3571 - 15
Main Authors Atyeo, Caroline G., Shook, Lydia L., Brigida, Sara, De Guzman, Rose M., Demidkin, Stepan, Muir, Cordelia, Akinwunmi, Babatunde, Baez, Arantxa Medina, Sheehan, Maegan L., McSweeney, Erin, Burns, Madeleine D., Nayak, Ruhi, Kumar, Maya K., Patel, Chinmay D., Fialkowski, Allison, Cvrk, Dana, Goldfarb, Ilona T., Yonker, Lael M., Fasano, Alessio, Balazs, Alejandro B., Elovitz, Michal A., Gray, Kathryn J., Alter, Galit, Edlow, Andrea G.
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 28.06.2022
Nature Publishing Group
Nature Portfolio
Subjects
13/1
13/31
631/250/2152/2153/1291
631/250/590
631/326/596/4130
Ad26COVS1
Antibodies
Antibodies, Viral
Antibody response
BNT162 Vaccine
Cell activation
Complement activation
Cord blood
Coronaviruses
COVID-19
COVID-19 - prevention & control
COVID-19 Vaccines
Fc receptors
Female
Humanities and Social Sciences
Humans
Immune response
Immune response (humoral)
Immune system
Immunity
Infant, Newborn
Leukocytes (neutrophilic)
Morbidity
mRNA
multidisciplinary
Neonates
Phagocytosis
Placenta
Platforms
Pregnancy
Pregnancy Complications, Infectious - prevention & control
SARS-CoV-2
Science
Science (multidisciplinary)
Serology
Severe acute respiratory syndrome coronavirus 2
Umbilical cord
United States
Vaccination - methods
Vaccines
United States
Online AccessGet full text

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Abstract The availability of three COVID-19 vaccines in the United States provides an unprecedented opportunity to examine how vaccine platforms and timing of vaccination in pregnancy impact maternal and neonatal immunity. Here, we characterize the antibody profile after Ad26.COV2.S, mRNA-1273 or BNT162b2 vaccination in 158 pregnant individuals and evaluate transplacental antibody transfer by profiling maternal and umbilical cord blood in 175 maternal-neonatal dyads. These analyses reveal lower vaccine-induced functions and Fc receptor-binding after Ad26.COV2.S compared to mRNA vaccination and subtle advantages in titer and function with mRNA-1273 versus BN162b2. mRNA vaccines have higher titers and functions against SARS-CoV-2 variants of concern. First and third trimester vaccination results in enhanced maternal antibody-dependent NK-cell activation, cellular and neutrophil phagocytosis, and complement deposition relative to second trimester. Higher transplacental transfer ratios following first and second trimester vaccination may reflect placental compensation for waning maternal titers. These results provide novel insight into the impact of platform and trimester of vaccination on maternal humoral immune response and transplacental antibody transfer. Pregnant individuals infected with SARS-CoV-2 are at high risk of morbidity and mortality, in addition to adverse pregnancy outcomes, yet little is known regarding trimester-specific immunity and maternal protection from COVID-19 vaccine platforms. Authors utilise a systems serology approach to characterise the material antibody response and the transplacental antibody transfer, dependent on vaccine platform and trimester of vaccination.
AbstractList The availability of three COVID-19 vaccines in the United States provides an unprecedented opportunity to examine how vaccine platforms and timing of vaccination in pregnancy impact maternal and neonatal immunity. Here, we characterize the antibody profile after Ad26.COV2.S, mRNA-1273 or BNT162b2 vaccination in 158 pregnant individuals and evaluate transplacental antibody transfer by profiling maternal and umbilical cord blood in 175 maternal-neonatal dyads. These analyses reveal lower vaccine-induced functions and Fc receptor-binding after Ad26.COV2.S compared to mRNA vaccination and subtle advantages in titer and function with mRNA-1273 versus BN162b2. mRNA vaccines have higher titers and functions against SARS-CoV-2 variants of concern. First and third trimester vaccination results in enhanced maternal antibody-dependent NK-cell activation, cellular and neutrophil phagocytosis, and complement deposition relative to second trimester. Higher transplacental transfer ratios following first and second trimester vaccination may reflect placental compensation for waning maternal titers. These results provide novel insight into the impact of platform and trimester of vaccination on maternal humoral immune response and transplacental antibody transfer. Pregnant individuals infected with SARS-CoV-2 are at high risk of morbidity and mortality, in addition to adverse pregnancy outcomes, yet little is known regarding trimester-specific immunity and maternal protection from COVID-19 vaccine platforms. Authors utilise a systems serology approach to characterise the material antibody response and the transplacental antibody transfer, dependent on vaccine platform and trimester of vaccination.
The availability of three COVID-19 vaccines in the United States provides an unprecedented opportunity to examine how vaccine platforms and timing of vaccination in pregnancy impact maternal and neonatal immunity. Here, we characterize the antibody profile after Ad26.COV2.S, mRNA-1273 or BNT162b2 vaccination in 158 pregnant individuals and evaluate transplacental antibody transfer by profiling maternal and umbilical cord blood in 175 maternal-neonatal dyads. These analyses reveal lower vaccine-induced functions and Fc receptor-binding after Ad26.COV2.S compared to mRNA vaccination and subtle advantages in titer and function with mRNA-1273 versus BN162b2. mRNA vaccines have higher titers and functions against SARS-CoV-2 variants of concern. First and third trimester vaccination results in enhanced maternal antibody-dependent NK-cell activation, cellular and neutrophil phagocytosis, and complement deposition relative to second trimester. Higher transplacental transfer ratios following first and second trimester vaccination may reflect placental compensation for waning maternal titers. These results provide novel insight into the impact of platform and trimester of vaccination on maternal humoral immune response and transplacental antibody transfer.
Pregnant individuals infected with SARS-CoV-2 are at high risk of morbidity and mortality, in addition to adverse pregnancy outcomes, yet little is known regarding trimester-specific immunity and maternal protection from COVID-19 vaccine platforms. Authors utilise a systems serology approach to characterise the material antibody response and the transplacental antibody transfer, dependent on vaccine platform and trimester of vaccination.
The availability of three COVID-19 vaccines in the United States provides an unprecedented opportunity to examine how vaccine platforms and timing of vaccination in pregnancy impact maternal and neonatal immunity. Here, we characterize the antibody profile after Ad26.COV2.S, mRNA-1273 or BNT162b2 vaccination in 158 pregnant individuals and evaluate transplacental antibody transfer by profiling maternal and umbilical cord blood in 175 maternal-neonatal dyads. These analyses reveal lower vaccine-induced functions and Fc receptor-binding after Ad26.COV2.S compared to mRNA vaccination and subtle advantages in titer and function with mRNA-1273 versus BN162b2. mRNA vaccines have higher titers and functions against SARS-CoV-2 variants of concern. First and third trimester vaccination results in enhanced maternal antibody-dependent NK-cell activation, cellular and neutrophil phagocytosis, and complement deposition relative to second trimester. Higher transplacental transfer ratios following first and second trimester vaccination may reflect placental compensation for waning maternal titers. These results provide novel insight into the impact of platform and trimester of vaccination on maternal humoral immune response and transplacental antibody transfer.Pregnant individuals infected with SARS-CoV-2 are at high risk of morbidity and mortality, in addition to adverse pregnancy outcomes, yet little is known regarding trimester-specific immunity and maternal protection from COVID-19 vaccine platforms. Authors utilise a systems serology approach to characterise the material antibody response and the transplacental antibody transfer, dependent on vaccine platform and trimester of vaccination.
The availability of three COVID-19 vaccines in the United States provides an unprecedented opportunity to examine how vaccine platforms and timing of vaccination in pregnancy impact maternal and neonatal immunity. Here, we characterize the antibody profile after Ad26.COV2.S, mRNA-1273 or BNT162b2 vaccination in 158 pregnant individuals and evaluate transplacental antibody transfer by profiling maternal and umbilical cord blood in 175 maternal-neonatal dyads. These analyses reveal lower vaccine-induced functions and Fc receptor-binding after Ad26.COV2.S compared to mRNA vaccination and subtle advantages in titer and function with mRNA-1273 versus BN162b2. mRNA vaccines have higher titers and functions against SARS-CoV-2 variants of concern. First and third trimester vaccination results in enhanced maternal antibody-dependent NK-cell activation, cellular and neutrophil phagocytosis, and complement deposition relative to second trimester. Higher transplacental transfer ratios following first and second trimester vaccination may reflect placental compensation for waning maternal titers. These results provide novel insight into the impact of platform and trimester of vaccination on maternal humoral immune response and transplacental antibody transfer.The availability of three COVID-19 vaccines in the United States provides an unprecedented opportunity to examine how vaccine platforms and timing of vaccination in pregnancy impact maternal and neonatal immunity. Here, we characterize the antibody profile after Ad26.COV2.S, mRNA-1273 or BNT162b2 vaccination in 158 pregnant individuals and evaluate transplacental antibody transfer by profiling maternal and umbilical cord blood in 175 maternal-neonatal dyads. These analyses reveal lower vaccine-induced functions and Fc receptor-binding after Ad26.COV2.S compared to mRNA vaccination and subtle advantages in titer and function with mRNA-1273 versus BN162b2. mRNA vaccines have higher titers and functions against SARS-CoV-2 variants of concern. First and third trimester vaccination results in enhanced maternal antibody-dependent NK-cell activation, cellular and neutrophil phagocytosis, and complement deposition relative to second trimester. Higher transplacental transfer ratios following first and second trimester vaccination may reflect placental compensation for waning maternal titers. These results provide novel insight into the impact of platform and trimester of vaccination on maternal humoral immune response and transplacental antibody transfer.
ArticleNumber 3571
Author Kumar, Maya K.
Fialkowski, Allison
Shook, Lydia L.
Balazs, Alejandro B.
Patel, Chinmay D.
De Guzman, Rose M.
Baez, Arantxa Medina
Yonker, Lael M.
Brigida, Sara
Atyeo, Caroline G.
Goldfarb, Ilona T.
Edlow, Andrea G.
Sheehan, Maegan L.
Cvrk, Dana
Nayak, Ruhi
Burns, Madeleine D.
Alter, Galit
Muir, Cordelia
Demidkin, Stepan
Elovitz, Michal A.
Gray, Kathryn J.
Fasano, Alessio
McSweeney, Erin
Akinwunmi, Babatunde
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  surname: Goldfarb
  fullname: Goldfarb, Ilona T.
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  organization: Department of Obstetrics & Gynecology, Massachusetts General Hospital, Harvard Medical School, Vincent Center for Reproductive Biology, Massachusetts General Hospital
BackLink https://www.ncbi.nlm.nih.gov/pubmed/35764643$$D View this record in MEDLINE/PubMed
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Cites_doi 10.3389/fmicb.2020.01499
10.1001/jama.2021.1865
10.1016/j.vaccine.2018.07.012
10.1038/s41590-021-01088-9
10.1093/eurheartj/ehab103
10.1097/INF.0b013e318193ead7
10.1001/jamapediatrics.2021.1050
10.1002/bdr2.1642
10.1097/AOG.0000000000004339
10.1126/science.abg5268
10.1056/NEJMc2115596
10.1001/jama.2021.7563
10.1093/humupd/dmu041
10.1093/infdis/jis592
10.1001/jama.2021.3645
10.1016/j.cell.2021.12.033
10.3389/fimmu.2020.575197
10.15585/mmwr.mm6944e3
10.1056/NEJMc2108829
10.1101/2021.03.11.21253352
10.1111/irv.12649
10.1016/j.ajogmf.2021.100467
10.1016/j.vaccine.2020.01.009
10.1001/jama.2021.11035
10.1038/s41586-021-03681-2
10.1155/2012/985646
10.1038/s41591-021-01377-8
10.1097/AOG.0000000000004621
10.1038/nri.2017.64
10.1093/cid/ciw027
10.1128/CVI.00131-10
10.1001/jama.2022.1190
10.1016/j.vaccine.2014.08.038
10.1093/infdis/jir026
10.15585/mmwr.mm7106a4
10.3389/fimmu.2017.01294
10.1097/AOG.0000000000002662
10.3389/fimmu.2019.02729
10.1001/jama.2014.3633
10.15585/mmwr.mm7047e1
10.1038/s41591-021-01490-8
10.15585/mmwr.mm6938e1
10.1097/AOG.0b013e31822e5c02
10.1056/NEJMc2113516
10.3389/fimmu.2021.637651
10.15585/mmwr.mm7107e3
10.1017/S0950268899002046
10.1016/S2666-5247(21)00267-6
10.15585/mmwr.mm7101e1
10.3389/fimmu.2020.01920
10.1001/jama.2018.14298
10.1016/j.cell.2019.05.044
10.1038/s41577-021-00578-z
10.1016/j.lanepe.2022.100313
10.1097/AOG.0000000000004438
10.1038/s41586-021-04387-1
10.5858/arpa.202-0029-SA
10.3390/antib9030038
10.1016/j.ajog.2021.03.035
10.1001/jama.2022.1206
10.1093/cid/ciab1041
10.3389/fimmu.2022.797589
10.1126/sciimmunol.aan2946
10.1084/jem.20202756
10.1016/j.ajog.2021.03.023
10.1101/2021.09.21.21262927
10.1126/scitranslmed.abi8631
10.1093/infdis/jiab593
10.1101/2021.05.11.443609
10.1097/AOG.0000000000004693
10.1038/s41591-022-01704-7
10.1056/NEJMc2113891
10.1172/jci.insight.157354
10.1097/AOG.0000000000003924
10.1038/s41591-021-01666-2
10.1056/NEJMoa2104983
10.1172/JCI150319
10.3390/ijerph18115613
10.1016/j.ajog.2021.08.007
10.1038/s41586-021-04389-z
10.1126/scitranslmed.abn7842
10.15585/mmwr.mm6944e2
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References Zambrano (CR1) 2020; 69
Shah, Canziani, Carter, Chaiken (CR43) 2021; 12
Sadarangani, Marchant, Kollmann (CR91) 2021; 21
Than, Hahn, Rossi, Szekeres-Bartho (CR32) 2019; 10
Abu Raya (CR65) 2014; 32
CR39
DeSisto (CR10) 2021; 70
Engjom (CR23) 2022; 13
CR37
Van Spall (CR14) 2021; 42
CR36
Clements (CR76) 2020; 11
CR34
CR77
Morgan (CR21) 2022; 139
Voss (CR42) 2021; 372
CR75
CR74
Cromer (CR48) 2022; 3
CR73
Halasa (CR29) 2022; 71
Faucette, Unger, Gonik, Chen (CR64) 2015; 21
Healy (CR78) 2018; 320
Wilcox, Holder, Jones (CR60) 2017; 8
Stephenson (CR70) 2021; 325
CR3
Metz (CR6) 2021; 137
Goldshtein (CR24) 2021; 326
CR5
Munoz (CR58) 2014; 311
Delahoy (CR4) 2020; 69
CR8
(CR31) 2018; 131
CR9
CR45
CR89
Saso, Kampmann (CR30) 2020; 11
CR44
CR88
Mor, Aldo, Alvero (CR33) 2017; 17
Khoury (CR47) 2021; 27
CR87
Lipkind (CR19) 2022; 71
CR86
Kerr, Van Bennekom, Mitchell (CR82) 2020; 112
Meaney-Delman, Ellington, Shimabukuro (CR38) 2021
CR40
Lambrou (CR49) 2022; 71
Heininger, Riffelmann, Leineweber, Wirsing von Koenig (CR57) 2009; 28
Rottenstreich (CR27) 2021
Collier (CR17) 2021; 325
Fortner (CR79) 2018; 36
Horiya (CR85) 2011; 118
CR18
CR16
CR15
Bianchi, Kaeser, Cernich (CR13) 2021; 325
CR12
CR11
CR55
CR54
CR53
CR52
CR51
Gonçalves (CR56) 1999; 122
CR50
Cuningham (CR66) 2019; 13
Metz (CR7) 2022; 327
Eberhardt (CR80) 2016; 62
Alter (CR71) 2021; 596
Villar (CR2) 2021; 175
Garcia-Beltran (CR92) 2022; 185
Barouch (CR72) 2021; 385
Collier (CR41) 2021; 385
CR28
Theiler (CR20) 2021; 3
CR26
Dagan (CR22) 2021; 27
CR25
CR69
CR68
Jennewein (CR61) 2019; 178
CR67
Abu-Raya, Michalski, Sadarangani, Lavoie (CR35) 2020; 11
Palmeira, Quinello, Silveira-Lessa, Zago, Carneiro-Sampaio (CR59) 2012; 2012
CR63
CR62
Ohfuji (CR83) 2011; 203
Schlaudecker, McNeal, Dodd, Ranz, Steinhoff (CR84) 2012; 206
Brewer (CR46) 2022; 23
Plotkin (CR90) 2010; 17
Hall (CR81) 2020; 38
A Saso (31169_CR30) 2020; 11
S Ohfuji (31169_CR83) 2011; 203
M Horiya (31169_CR85) 2011; 118
WN Voss (31169_CR42) 2021; 372
DH Barouch (31169_CR72) 2021; 385
J Villar (31169_CR2) 2021; 175
NG Than (31169_CR32) 2019; 10
G Gonçalves (31169_CR56) 1999; 122
RC Brewer (31169_CR46) 2022; 23
U Heininger (31169_CR57) 2009; 28
A-RY Collier (31169_CR41) 2021; 385
D Cromer (31169_CR48) 2022; 3
CR Wilcox (31169_CR60) 2017; 8
P Palmeira (31169_CR59) 2012; 2012
MJ Delahoy (31169_CR4) 2020; 69
NB Halasa (31169_CR29) 2022; 71
31169_CR75
31169_CR74
31169_CR73
31169_CR36
TD Metz (31169_CR7) 2022; 327
I Goldshtein (31169_CR24) 2021; 326
31169_CR34
31169_CR77
TD Metz (31169_CR6) 2021; 137
31169_CR39
FM Munoz (31169_CR58) 2014; 311
31169_CR37
DS Khoury (31169_CR47) 2021; 27
CL DeSisto (31169_CR10) 2021; 70
G Mor (31169_CR33) 2017; 17
T Clements (31169_CR76) 2020; 11
N Dagan (31169_CR22) 2021; 27
CS Eberhardt (31169_CR80) 2016; 62
WF Garcia-Beltran (31169_CR92) 2022; 185
C Hall (31169_CR81) 2020; 38
JA Morgan (31169_CR21) 2022; 139
AS Lambrou (31169_CR49) 2022; 71
31169_CR87
31169_CR86
31169_CR40
CM Healy (31169_CR78) 2018; 320
ACOG Immunization, Infectious Disease, and Public Health Preparedness Expert Working Group. (31169_CR31) 2018; 131
31169_CR3
31169_CR45
31169_CR89
31169_CR44
31169_CR88
31169_CR5
HS Lipkind (31169_CR19) 2022; 71
LD Zambrano (31169_CR1) 2020; 69
31169_CR8
P Shah (31169_CR43) 2021; 12
31169_CR9
B Abu Raya (31169_CR65) 2014; 32
31169_CR50
MF Jennewein (31169_CR61) 2019; 178
AN Faucette (31169_CR64) 2015; 21
31169_CR54
31169_CR53
31169_CR52
31169_CR51
31169_CR12
31169_CR11
31169_CR55
31169_CR18
31169_CR16
SM Kerr (31169_CR82) 2020; 112
31169_CR15
H Engjom (31169_CR23) 2022; 13
A Rottenstreich (31169_CR27) 2021
KE Stephenson (31169_CR70) 2021; 325
HGC Van Spall (31169_CR14) 2021; 42
A-RY Collier (31169_CR17) 2021; 325
G Alter (31169_CR71) 2021; 596
M Sadarangani (31169_CR91) 2021; 21
W Cuningham (31169_CR66) 2019; 13
KB Fortner (31169_CR79) 2018; 36
RN Theiler (31169_CR20) 2021; 3
B Abu-Raya (31169_CR35) 2020; 11
SA Plotkin (31169_CR90) 2010; 17
31169_CR63
31169_CR62
31169_CR25
DM Meaney-Delman (31169_CR38) 2021
31169_CR69
31169_CR68
31169_CR67
EP Schlaudecker (31169_CR84) 2012; 206
31169_CR28
DW Bianchi (31169_CR13) 2021; 325
31169_CR26
References_xml – ident: CR45
– volume: 11
  start-page: 1499
  year: 2020
  ident: CR30
  article-title: Maternal immunization: nature meets nurture
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2020.01499
– volume: 325
  start-page: 1041
  year: 2021
  end-page: 1042
  ident: CR13
  article-title: Involving pregnant individuals in clinical research on COVID-19 vaccines
  publication-title: JAMA
  doi: 10.1001/jama.2021.1865
– ident: CR68
– ident: CR74
– volume: 36
  start-page: 6354
  year: 2018
  end-page: 6360
  ident: CR79
  article-title: Reactogenicity and immunogenicity of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap) in pregnant and nonpregnant women
  publication-title: Vaccine
  doi: 10.1016/j.vaccine.2018.07.012
– volume: 23
  start-page: 33
  year: 2022
  end-page: 39
  ident: CR46
  article-title: BNT162b2 vaccine induces divergent B cell responses to SARS-CoV-2 S1 and S2
  publication-title: Nat. Immunol.
  doi: 10.1038/s41590-021-01088-9
– ident: CR39
– ident: CR87
– ident: CR16
– volume: 42
  start-page: 2724
  year: 2021
  end-page: 2726
  ident: CR14
  article-title: Exclusion of pregnant and lactating women from COVID-19 vaccine trials: a missed opportunity
  publication-title: Eur. Heart J.
  doi: 10.1093/eurheartj/ehab103
– ident: CR51
– ident: CR12
– volume: 28
  start-page: 443
  year: 2009
  end-page: 445
  ident: CR57
  article-title: Maternally derived antibodies against Bordetella pertussis antigens pertussis toxin and filamentous hemagglutinin in preterm and full term newborns
  publication-title: Pediatr. Infect. Dis. J.
  doi: 10.1097/INF.0b013e318193ead7
– volume: 175
  start-page: 817
  year: 2021
  end-page: 826
  ident: CR2
  article-title: Maternal and neonatal morbidity and mortality among pregnant women with and without COVID-19 infection: the INTERCOVID multinational cohort study
  publication-title: JAMA Pediatr.
  doi: 10.1001/jamapediatrics.2021.1050
– volume: 112
  start-page: 393
  year: 2020
  end-page: 403
  ident: CR82
  article-title: Tetanus, diphtheria, and pertussis vaccine (Tdap) in pregnancy and risk of major birth defects in the offspring
  publication-title: Birth Defects Res.
  doi: 10.1002/bdr2.1642
– ident: CR54
– volume: 137
  start-page: 571
  year: 2021
  end-page: 580
  ident: CR6
  article-title: Disease severity and perinatal outcomes of pregnant patients with coronavirus disease 2019 (COVID-19)
  publication-title: Obstet. Gynecol.
  doi: 10.1097/AOG.0000000000004339
– volume: 372
  start-page: 1108
  year: 2021
  end-page: 1112
  ident: CR42
  article-title: Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes
  publication-title: Science
  doi: 10.1126/science.abg5268
– ident: CR77
– ident: CR8
– ident: CR25
– volume: 385
  start-page: 2010
  year: 2021
  end-page: 2012
  ident: CR41
  article-title: Differential kinetics of immune responses elicited by Covid-19 vaccines
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJMc2115596
– volume: 325
  start-page: 2370
  year: 2021
  end-page: 2380
  ident: CR17
  article-title: Immunogenicity of COVID-19 mRNA vaccines in pregnant and lactating women
  publication-title: JAMA
  doi: 10.1001/jama.2021.7563
– volume: 21
  start-page: 119
  year: 2015
  end-page: 135
  ident: CR64
  article-title: Maternal vaccination: moving the science forward
  publication-title: Hum. Reprod. Update
  doi: 10.1093/humupd/dmu041
– volume: 206
  start-page: 1670
  year: 2012
  end-page: 1673
  ident: CR84
  article-title: Pregnancy modifies the antibody response to trivalent influenza immunization
  publication-title: J. Infect. Dis.
  doi: 10.1093/infdis/jis592
– volume: 325
  start-page: 1535
  year: 2021
  end-page: 1544
  ident: CR70
  article-title: Immunogenicity of the Ad26.COV2.S vaccine for COVID-19
  publication-title: JAMA
  doi: 10.1001/jama.2021.3645
– volume: 185
  start-page: 457
  year: 2022
  end-page: 466.e4
  ident: CR92
  article-title: mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant
  publication-title: Cell
  doi: 10.1016/j.cell.2021.12.033
– ident: CR67
– ident: CR75
– volume: 11
  start-page: 575197
  year: 2020
  ident: CR35
  article-title: Maternal immunological adaptation during normal pregnancy
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2020.575197
– ident: CR15
– ident: CR88
– volume: 69
  start-page: 1641
  year: 2020
  end-page: 1647
  ident: CR1
  article-title: Update: characteristics of symptomatic women of reproductive age with laboratory-confirmed SARS-CoV-2 infection by pregnancy status - United States, January 22-October 3, 2020
  publication-title: MMWR Morb. Mortal. Wkly. Rep.
  doi: 10.15585/mmwr.mm6944e3
– ident: CR50
– volume: 385
  start-page: 951
  year: 2021
  end-page: 953
  ident: CR72
  article-title: Durable humoral and cellular immune responses 8 months after Ad26.COV2.S vaccination
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJMc2108829
– year: 2021
  ident: CR27
  article-title: Efficient maternofetal transplacental transfer of anti- SARS-CoV-2 spike antibodies after antenatal SARS-CoV-2 BNT162b2 mRNA vaccination
  publication-title: bioRxiv
  doi: 10.1101/2021.03.11.21253352
– volume: 13
  start-page: 438
  year: 2019
  end-page: 452
  ident: CR66
  article-title: Optimal timing of influenza vaccine during pregnancy: a systematic review and meta-analysis
  publication-title: Influenza Other Respi. Viruses
  doi: 10.1111/irv.12649
– ident: CR11
– ident: CR9
– volume: 3
  start-page: 100467
  year: 2021
  ident: CR20
  article-title: Pregnancy and birth outcomes after SARS-CoV-2 vaccination in pregnancy
  publication-title: Am. J. Obstet. Gynecol. MFM
  doi: 10.1016/j.ajogmf.2021.100467
– ident: CR36
– volume: 38
  start-page: 1982
  year: 2020
  end-page: 1988
  ident: CR81
  article-title: Safety of tetanus, diphtheria, and acellular pertussis vaccination among pregnant active duty U.S. military women
  publication-title: Vaccine
  doi: 10.1016/j.vaccine.2020.01.009
– ident: CR5
– volume: 326
  start-page: 728
  year: 2021
  end-page: 735
  ident: CR24
  article-title: Association between BNT162b2 vaccination and incidence of SARS-CoV-2 infection in pregnant women
  publication-title: JAMA
  doi: 10.1001/jama.2021.11035
– volume: 596
  start-page: 268
  year: 2021
  end-page: 272
  ident: CR71
  article-title: Immunogenicity of Ad26.COV2.S vaccine against SARS-CoV-2 variants in humans
  publication-title: Nature
  doi: 10.1038/s41586-021-03681-2
– volume: 2012
  start-page: 985646
  year: 2012
  ident: CR59
  article-title: IgG placental transfer in healthy and pathological pregnancies
  publication-title: Clin. Dev. Immunol.
  doi: 10.1155/2012/985646
– ident: CR26
– volume: 27
  start-page: 1205
  year: 2021
  end-page: 1211
  ident: CR47
  article-title: Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection
  publication-title: Nat. Med.
  doi: 10.1038/s41591-021-01377-8
– volume: 139
  start-page: 107
  year: 2022
  end-page: 109
  ident: CR21
  article-title: Maternal outcomes after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in vaccinated compared with unvaccinated pregnant patients
  publication-title: Obstet. Gynecol.
  doi: 10.1097/AOG.0000000000004621
– ident: CR18
– volume: 17
  start-page: 469
  year: 2017
  end-page: 482
  ident: CR33
  article-title: The unique immunological and microbial aspects of pregnancy
  publication-title: Nat. Rev. Immunol.
  doi: 10.1038/nri.2017.64
– volume: 62
  start-page: 829
  year: 2016
  end-page: 836
  ident: CR80
  article-title: Maternal immunization earlier in pregnancy maximizes antibody transfer and expected infant seropositivity against pertussis
  publication-title: Clin. Infect. Dis.
  doi: 10.1093/cid/ciw027
– volume: 17
  start-page: 1055
  year: 2010
  end-page: 1065
  ident: CR90
  article-title: Correlates of protection induced by vaccination
  publication-title: Clin. Vaccine Immunol.
  doi: 10.1128/CVI.00131-10
– volume: 327
  start-page: 748
  year: 2022
  end-page: 759
  ident: CR7
  article-title: Association of SARS-CoV-2 infection with serious maternal morbidity and mortality from obstetric complications
  publication-title: JAMA
  doi: 10.1001/jama.2022.1190
– volume: 32
  start-page: 5787
  year: 2014
  end-page: 5793
  ident: CR65
  article-title: The effect of timing of maternal tetanus, diphtheria, and acellular pertussis (Tdap) immunization during pregnancy on newborn pertussis antibody levels - a prospective study
  publication-title: Vaccine
  doi: 10.1016/j.vaccine.2014.08.038
– volume: 203
  start-page: 1301
  year: 2011
  end-page: 1308
  ident: CR83
  article-title: Immunogenicity of a monovalent 2009 influenza A (H1N1) vaccine among pregnant women: lowered antibody response by prior seasonal vaccination
  publication-title: J. Infect. Dis.
  doi: 10.1093/infdis/jir026
– ident: CR37
– volume: 71
  start-page: 206
  year: 2022
  end-page: 211
  ident: CR49
  article-title: Genomic surveillance for SARS-CoV-2 variants: predominance of the delta (B.1.617.2) and Omicron (B.1.1.529) variants - United States, June 2021-January 2022
  publication-title: MMWR Morb. Mortal. Wkly. Rep.
  doi: 10.15585/mmwr.mm7106a4
– ident: CR53
– volume: 8
  start-page: 1294
  year: 2017
  ident: CR60
  article-title: Factors affecting the FcRn-mediated transplacental transfer of antibodies and implications for vaccination in pregnancy
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2017.01294
– ident: CR89
– volume: 131
  start-page: e214
  year: 2018
  end-page: e217
  ident: CR31
  article-title: ACOG committee opinion: maternal immunization
  publication-title: Obstet. Gynecol.
  doi: 10.1097/AOG.0000000000002662
– volume: 10
  start-page: 2729
  year: 2019
  ident: CR32
  article-title: Editorial: fetal-maternal immune interactions in pregnancy
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2019.02729
– volume: 311
  start-page: 1760
  year: 2014
  end-page: 1769
  ident: CR58
  article-title: Safety and immunogenicity of tetanus diphtheria and acellular pertussis (Tdap) immunization during pregnancy in mothers and infants: a randomized clinical trial
  publication-title: JAMA
  doi: 10.1001/jama.2014.3633
– volume: 70
  start-page: 1640
  year: 2021
  end-page: 1645
  ident: CR10
  article-title: Risk for stillbirth among women with and without COVID-19 at delivery hospitalization - United States, March 2020-September 2021
  publication-title: MMWR Morb. Mortal. Wkly. Rep.
  doi: 10.15585/mmwr.mm7047e1
– volume: 27
  start-page: 1693
  year: 2021
  end-page: 1695
  ident: CR22
  article-title: Effectiveness of the BNT162b2 mRNA COVID-19 vaccine in pregnancy
  publication-title: Nat. Med.
  doi: 10.1038/s41591-021-01490-8
– ident: CR86
– ident: CR40
– ident: CR63
– volume: 69
  start-page: 1347
  year: 2020
  end-page: 1354
  ident: CR4
  article-title: Characteristics and maternal and birth outcomes of hospitalized pregnant women with laboratory-confirmed COVID-19 - COVID-NET, 13 states, March 1-August 22, 2020
  publication-title: MMWR Morb. Mortal. Wkly. Rep.
  doi: 10.15585/mmwr.mm6938e1
– volume: 118
  start-page: 887
  year: 2011
  end-page: 894
  ident: CR85
  article-title: Efficacy of double vaccination with the 2009 pandemic influenza A (H1N1) vaccine during pregnancy
  publication-title: Obstet. Gynecol.
  doi: 10.1097/AOG.0b013e31822e5c02
– year: 2021
  ident: CR38
  article-title: On preliminary findings of mRNA Covid-19 vaccine safety in pregnant persons. Reply
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJMc2113516
– ident: CR69
– ident: CR44
– volume: 12
  start-page: 637651
  year: 2021
  ident: CR43
  article-title: The case for S2: the potential benefits of the S2 subunit of the SARS-CoV-2 spike protein as an immunogen in fighting the COVID-19 pandemic
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2021.637651
– ident: CR73
– volume: 71
  start-page: 264
  year: 2022
  end-page: 270
  ident: CR29
  article-title: Effectiveness of maternal vaccination with mRNA COVID-19 vaccine during pregnancy against COVID-19-associated hospitalization in infants aged <6 months - 17 states, July 2021-January 2022
  publication-title: MMWR Morb. Mortal. Wkly. Rep.
  doi: 10.15585/mmwr.mm7107e3
– volume: 122
  start-page: 273
  year: 1999
  end-page: 279
  ident: CR56
  article-title: Transplacental transfer of measles and total IgG
  publication-title: Epidemiol. Infect.
  doi: 10.1017/S0950268899002046
– ident: CR3
– volume: 3
  start-page: e52
  year: 2022
  end-page: e61
  ident: CR48
  article-title: Neutralising antibody titres as predictors of protection against SARS-CoV-2 variants and the impact of boosting: a meta-analysis
  publication-title: Lancet Microbe
  doi: 10.1016/S2666-5247(21)00267-6
– ident: CR52
– volume: 71
  start-page: 26
  year: 2022
  end-page: 30
  ident: CR19
  article-title: Receipt of COVID-19 vaccine during pregnancy and preterm or small-for-gestational-age at birth - eight integrated health care organizations, United States, December 15, 2020-July 22, 2021
  publication-title: MMWR Morb. Mortal. Wkly. Rep.
  doi: 10.15585/mmwr.mm7101e1
– volume: 11
  start-page: 1920
  year: 2020
  ident: CR76
  article-title: Update on transplacental transfer of IgG subclasses: impact of maternal and fetal factors
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2020.01920
– ident: CR34
– volume: 320
  start-page: 1464
  year: 2018
  end-page: 1470
  ident: CR78
  article-title: Association between third-trimester tdap immunization and neonatal pertussis antibody concentration
  publication-title: JAMA
  doi: 10.1001/jama.2018.14298
– volume: 178
  start-page: 202
  year: 2019
  end-page: 215.e14
  ident: CR61
  article-title: Fc glycan-mediated regulation of placental antibody transfer
  publication-title: Cell
  doi: 10.1016/j.cell.2019.05.044
– ident: CR55
– ident: CR28
– ident: CR62
– volume: 21
  start-page: 475
  year: 2021
  end-page: 484
  ident: CR91
  article-title: Immunological mechanisms of vaccine-induced protection against COVID-19 in humans
  publication-title: Nat. Rev. Immunol.
  doi: 10.1038/s41577-021-00578-z
– volume: 13
  start-page: 100313
  year: 2022
  ident: CR23
  article-title: Severe COVID-19 in pregnancy is almost exclusively limited to unvaccinated women - time for policies to change
  publication-title: Lancet Reg. Health Eur.
  doi: 10.1016/j.lanepe.2022.100313
– ident: 31169_CR25
  doi: 10.1097/AOG.0000000000004438
– ident: 31169_CR54
  doi: 10.1038/s41586-021-04387-1
– volume: 206
  start-page: 1670
  year: 2012
  ident: 31169_CR84
  publication-title: J. Infect. Dis.
  doi: 10.1093/infdis/jis592
– ident: 31169_CR8
  doi: 10.5858/arpa.202-0029-SA
– volume: 13
  start-page: 100313
  year: 2022
  ident: 31169_CR23
  publication-title: Lancet Reg. Health Eur.
  doi: 10.1016/j.lanepe.2022.100313
– volume: 372
  start-page: 1108
  year: 2021
  ident: 31169_CR42
  publication-title: Science
  doi: 10.1126/science.abg5268
– ident: 31169_CR63
  doi: 10.3390/antib9030038
– year: 2021
  ident: 31169_CR38
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJMc2113516
– volume: 327
  start-page: 748
  year: 2022
  ident: 31169_CR7
  publication-title: JAMA
  doi: 10.1001/jama.2022.1190
– ident: 31169_CR26
  doi: 10.1016/j.ajog.2021.03.035
– ident: 31169_CR86
  doi: 10.1001/jama.2022.1206
– ident: 31169_CR77
– volume: 131
  start-page: e214
  year: 2018
  ident: 31169_CR31
  publication-title: Obstet. Gynecol.
  doi: 10.1097/AOG.0000000000002662
– ident: 31169_CR11
– volume: 326
  start-page: 728
  year: 2021
  ident: 31169_CR24
  publication-title: JAMA
  doi: 10.1001/jama.2021.11035
– volume: 11
  start-page: 1920
  year: 2020
  ident: 31169_CR76
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2020.01920
– volume: 385
  start-page: 2010
  year: 2021
  ident: 31169_CR41
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJMc2115596
– volume: 203
  start-page: 1301
  year: 2011
  ident: 31169_CR83
  publication-title: J. Infect. Dis.
  doi: 10.1093/infdis/jir026
– ident: 31169_CR52
  doi: 10.1093/cid/ciab1041
– ident: 31169_CR67
  doi: 10.3389/fimmu.2022.797589
– volume: 10
  start-page: 2729
  year: 2019
  ident: 31169_CR32
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2019.02729
– volume: 17
  start-page: 469
  year: 2017
  ident: 31169_CR33
  publication-title: Nat. Rev. Immunol.
  doi: 10.1038/nri.2017.64
– ident: 31169_CR34
  doi: 10.1126/sciimmunol.aan2946
– volume: 139
  start-page: 107
  year: 2022
  ident: 31169_CR21
  publication-title: Obstet. Gynecol.
  doi: 10.1097/AOG.0000000000004621
– volume: 8
  start-page: 1294
  year: 2017
  ident: 31169_CR60
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2017.01294
– ident: 31169_CR73
  doi: 10.1084/jem.20202756
– ident: 31169_CR15
  doi: 10.1016/j.ajog.2021.03.023
– volume: 27
  start-page: 1205
  year: 2021
  ident: 31169_CR47
  publication-title: Nat. Med.
  doi: 10.1038/s41591-021-01377-8
– volume: 122
  start-page: 273
  year: 1999
  ident: 31169_CR56
  publication-title: Epidemiol. Infect.
  doi: 10.1017/S0950268899002046
– volume: 385
  start-page: 951
  year: 2021
  ident: 31169_CR72
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJMc2108829
– volume: 175
  start-page: 817
  year: 2021
  ident: 31169_CR2
  publication-title: JAMA Pediatr.
  doi: 10.1001/jamapediatrics.2021.1050
– ident: 31169_CR39
  doi: 10.1101/2021.09.21.21262927
– volume: 32
  start-page: 5787
  year: 2014
  ident: 31169_CR65
  publication-title: Vaccine
  doi: 10.1016/j.vaccine.2014.08.038
– volume: 118
  start-page: 887
  year: 2011
  ident: 31169_CR85
  publication-title: Obstet. Gynecol.
  doi: 10.1097/AOG.0b013e31822e5c02
– ident: 31169_CR16
  doi: 10.1126/scitranslmed.abi8631
– ident: 31169_CR69
  doi: 10.1093/infdis/jiab593
– volume: 23
  start-page: 33
  year: 2022
  ident: 31169_CR46
  publication-title: Nat. Immunol.
  doi: 10.1038/s41590-021-01088-9
– volume: 178
  start-page: 202
  year: 2019
  ident: 31169_CR61
  publication-title: Cell
  doi: 10.1016/j.cell.2019.05.044
– ident: 31169_CR44
  doi: 10.1101/2021.05.11.443609
– ident: 31169_CR87
– volume: 69
  start-page: 1641
  year: 2020
  ident: 31169_CR1
  publication-title: MMWR Morb. Mortal. Wkly. Rep.
  doi: 10.15585/mmwr.mm6944e3
– ident: 31169_CR62
– ident: 31169_CR40
  doi: 10.1093/infdis/jiab593
– ident: 31169_CR89
  doi: 10.1097/AOG.0000000000004693
– volume: 325
  start-page: 1041
  year: 2021
  ident: 31169_CR13
  publication-title: JAMA
  doi: 10.1001/jama.2021.1865
– ident: 31169_CR45
– volume: 69
  start-page: 1347
  year: 2020
  ident: 31169_CR4
  publication-title: MMWR Morb. Mortal. Wkly. Rep.
  doi: 10.15585/mmwr.mm6938e1
– volume: 42
  start-page: 2724
  year: 2021
  ident: 31169_CR14
  publication-title: Eur. Heart J.
  doi: 10.1093/eurheartj/ehab103
– volume: 185
  start-page: 457
  year: 2022
  ident: 31169_CR92
  publication-title: Cell
  doi: 10.1016/j.cell.2021.12.033
– volume: 36
  start-page: 6354
  year: 2018
  ident: 31169_CR79
  publication-title: Vaccine
  doi: 10.1016/j.vaccine.2018.07.012
– volume: 71
  start-page: 206
  year: 2022
  ident: 31169_CR49
  publication-title: MMWR Morb. Mortal. Wkly. Rep.
  doi: 10.15585/mmwr.mm7106a4
– volume: 596
  start-page: 268
  year: 2021
  ident: 31169_CR71
  publication-title: Nature
  doi: 10.1038/s41586-021-03681-2
– volume: 112
  start-page: 393
  year: 2020
  ident: 31169_CR82
  publication-title: Birth Defects Res.
  doi: 10.1002/bdr2.1642
– ident: 31169_CR75
– ident: 31169_CR55
  doi: 10.1038/s41591-022-01704-7
– volume: 17
  start-page: 1055
  year: 2010
  ident: 31169_CR90
  publication-title: Clin. Vaccine Immunol.
  doi: 10.1128/CVI.00131-10
– volume: 21
  start-page: 475
  year: 2021
  ident: 31169_CR91
  publication-title: Nat. Rev. Immunol.
  doi: 10.1038/s41577-021-00578-z
– ident: 31169_CR36
  doi: 10.1056/NEJMc2113891
– volume: 11
  start-page: 575197
  year: 2020
  ident: 31169_CR35
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2020.575197
– volume: 12
  start-page: 637651
  year: 2021
  ident: 31169_CR43
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2021.637651
– ident: 31169_CR50
  doi: 10.1172/jci.insight.157354
– volume: 28
  start-page: 443
  year: 2009
  ident: 31169_CR57
  publication-title: Pediatr. Infect. Dis. J.
  doi: 10.1097/INF.0b013e318193ead7
– ident: 31169_CR12
  doi: 10.1097/AOG.0000000000003924
– ident: 31169_CR9
  doi: 10.1038/s41591-021-01666-2
– ident: 31169_CR18
  doi: 10.1056/NEJMoa2104983
– volume: 2012
  start-page: 985646
  year: 2012
  ident: 31169_CR59
  publication-title: Clin. Dev. Immunol.
  doi: 10.1155/2012/985646
– volume: 325
  start-page: 2370
  year: 2021
  ident: 31169_CR17
  publication-title: JAMA
  doi: 10.1001/jama.2021.7563
– volume: 71
  start-page: 264
  year: 2022
  ident: 31169_CR29
  publication-title: MMWR Morb. Mortal. Wkly. Rep.
  doi: 10.15585/mmwr.mm7107e3
– ident: 31169_CR88
– volume: 27
  start-page: 1693
  year: 2021
  ident: 31169_CR22
  publication-title: Nat. Med.
  doi: 10.1038/s41591-021-01490-8
– volume: 311
  start-page: 1760
  year: 2014
  ident: 31169_CR58
  publication-title: JAMA
  doi: 10.1001/jama.2014.3633
– volume: 62
  start-page: 829
  year: 2016
  ident: 31169_CR80
  publication-title: Clin. Infect. Dis.
  doi: 10.1093/cid/ciw027
– volume: 38
  start-page: 1982
  year: 2020
  ident: 31169_CR81
  publication-title: Vaccine
  doi: 10.1016/j.vaccine.2020.01.009
– volume: 70
  start-page: 1640
  year: 2021
  ident: 31169_CR10
  publication-title: MMWR Morb. Mortal. Wkly. Rep.
  doi: 10.15585/mmwr.mm7047e1
– volume: 3
  start-page: e52
  year: 2022
  ident: 31169_CR48
  publication-title: Lancet Microbe
  doi: 10.1016/S2666-5247(21)00267-6
– ident: 31169_CR28
  doi: 10.1172/JCI150319
– volume: 13
  start-page: 438
  year: 2019
  ident: 31169_CR66
  publication-title: Influenza Other Respi. Viruses
  doi: 10.1111/irv.12649
– volume: 3
  start-page: 100467
  year: 2021
  ident: 31169_CR20
  publication-title: Am. J. Obstet. Gynecol. MFM
  doi: 10.1016/j.ajogmf.2021.100467
– volume: 137
  start-page: 571
  year: 2021
  ident: 31169_CR6
  publication-title: Obstet. Gynecol.
  doi: 10.1097/AOG.0000000000004339
– volume: 21
  start-page: 119
  year: 2015
  ident: 31169_CR64
  publication-title: Hum. Reprod. Update
  doi: 10.1093/humupd/dmu041
– ident: 31169_CR74
– volume: 325
  start-page: 1535
  year: 2021
  ident: 31169_CR70
  publication-title: JAMA
  doi: 10.1001/jama.2021.3645
– ident: 31169_CR3
  doi: 10.3390/ijerph18115613
– ident: 31169_CR37
  doi: 10.1016/j.ajog.2021.08.007
– ident: 31169_CR53
  doi: 10.1038/s41586-021-04389-z
– ident: 31169_CR51
  doi: 10.1126/scitranslmed.abn7842
– volume: 11
  start-page: 1499
  year: 2020
  ident: 31169_CR30
  publication-title: Front. Microbiol.
  doi: 10.3389/fmicb.2020.01499
– volume: 320
  start-page: 1464
  year: 2018
  ident: 31169_CR78
  publication-title: JAMA
  doi: 10.1001/jama.2018.14298
– ident: 31169_CR68
– ident: 31169_CR5
  doi: 10.15585/mmwr.mm6944e2
– year: 2021
  ident: 31169_CR27
  publication-title: bioRxiv
  doi: 10.1101/2021.03.11.21253352
– volume: 71
  start-page: 26
  year: 2022
  ident: 31169_CR19
  publication-title: MMWR Morb. Mortal. Wkly. Rep.
  doi: 10.15585/mmwr.mm7101e1
SSID ssj0000391844
Score 2.5951653
Snippet The availability of three COVID-19 vaccines in the United States provides an unprecedented opportunity to examine how vaccine platforms and timing of...
Pregnant individuals infected with SARS-CoV-2 are at high risk of morbidity and mortality, in addition to adverse pregnancy outcomes, yet little is known...
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StartPage 3571
SubjectTerms 13/1
13/31
631/250/2152/2153/1291
631/250/590
631/326/596/4130
Ad26COVS1
Antibodies
Antibodies, Viral
Antibody response
BNT162 Vaccine
Cell activation
Complement activation
Cord blood
Coronaviruses
COVID-19
COVID-19 - prevention & control
COVID-19 Vaccines
Fc receptors
Female
Humanities and Social Sciences
Humans
Immune response
Immune response (humoral)
Immune system
Immunity
Infant, Newborn
Leukocytes (neutrophilic)
Morbidity
mRNA
multidisciplinary
Neonates
Phagocytosis
Placenta
Platforms
Pregnancy
Pregnancy Complications, Infectious - prevention & control
SARS-CoV-2
Science
Science (multidisciplinary)
Serology
Severe acute respiratory syndrome coronavirus 2
Umbilical cord
United States
Vaccination - methods
Vaccines
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Title Maternal immune response and placental antibody transfer after COVID-19 vaccination across trimester and platforms
URI https://link.springer.com/article/10.1038/s41467-022-31169-8
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Volume 13
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