Creatinine monitoring patterns in the setting of direct oral anticoagulant therapy for non-valvular atrial fibrillation

• Published in: Journal of thrombosis and thrombolysis Vol. 48; no. 3; pp. 500 - 505
• Main Authors: Gruca, Martin M., Li, Yun, Kong, Xiaowen, DeCamillo, Deborah, Kline-Rogers, Eva, Ali, Mona A., Kaatz, Scott, Dahu, Musa, Froehlich, James B., Barnes, Geoffrey D.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.10.2019; Springer Nature B.V
• Subjects: Aged; Anticoagulants; Atrial Fibrillation - complications; Atrial Fibrillation - drug therapy; Cardiac arrhythmia; Cardiology; Creatinine; Creatinine - blood; Creatinine - pharmacokinetics; Drug Monitoring - methods; Drug Monitoring - standards; Factor Xa Inhibitors - adverse effects; Factor Xa Inhibitors - therapeutic use; Female; Fibrillation; Health risk assessment; Hematology; Humans; Kidney Diseases - complications; Male; Medicine; Medicine & Public Health; Michigan; Middle Aged; Population studies; Quality control; Renal function; Retrospective Studies; Stroke; Stroke - prevention & control; Michigan; Creatinine; Drug monitoring; Kidney diseases; Atrial fibrillation; Factor Xa inhibitors

Guidelines and experts note that patients with atrial fibrillation require regular renal function monitoring to ensure safe use of direct oral anticoagulants (DOACs). Insufficient monitoring could lead to inappropriate dosing and adverse events. Our objective was to describe the frequency of insuffi...