LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development - Vinckier, Nicholas K.; Patel, Nisha A.; Geusz, Ryan J.; Wang, Allen; Wang, Jinzhao; Matta, Ileana; Harrington, Austin R.; Wortham, Matthew; Wetton, Nichole; Wang, Jianxun; Jhala, Ulupi S.; Rosenfeld, Michael G.; et al. (Nature communications, 2020)
Keywords: 13; 13/109; 13/31; 13/51; 13/89; 38; 38/1; 38/15; 38/22; 38/39; 38/77; 38/88; 38/90; 38/91; 631/136; 631/136/142; 631/136/532; 631/337/176; 64; 64/60; Adult; Animals; Base Sequence; Cell differentiation; Cell Differentiation - drug effects; Differentiation (biology); Endocrine Cells - cytology; Endocrine Cells - drug effects; Endocrine Cells - metabolism; Enhancer Elements, Genetic - genetics; Enhancers; Epigenetics; Female; Gene expression; Gene Expression Regulation, Developmental - drug effects; Gene Silencing - drug effects; Histone Demethylases - metabolism; Histones; Human Embryonic Stem Cells - cytology; Human Embryonic Stem Cells - drug effects; Human Embryonic Stem Cells - metabolism; Humanities and Social Sciences; Humans; Intermediates; Islets of Langerhans - cytology; Islets of Langerhans - embryology; Male; Mice; multidisciplinary; Pancreas; Phenotypes; Retinoic acid; Science; Science (multidisciplinary); Signal Transduction - drug effects; Signaling; Transcription; Transcription Factors - metabolism; Tretinoin - metabolism; Tretinoin - pharmacology; Young Adult