Losartan Added to β-Blockade Therapy for Aortic Root Dilation in Marfan Syndrome: A Randomized, Open-Label Pilot Study - Chiu, Hsin-Hui; Wu, Mei-Hwan; Wang, Jou-Kou; Lu, Chun-Wei; Chiu, Shuenn-Nan; Chen, Chun-An; Lin, Ming-Tai; Hu, Fu-Chang (Mayo Clinic proceedings, 2013)
Keywords: Adolescent; Adrenergic beta blockers; Adrenergic beta-1 Receptor Antagonists - therapeutic use; Angiotensin II Type 1 Receptor Blockers - therapeutic use; Aortic Diseases - drug therapy; Aortic Diseases - etiology; Atenolol - therapeutic use; Child; Dilatation, Pathologic - drug therapy; Dilatation, Pathologic - etiology; Drug Administration Schedule; Drug therapy; Drug Therapy, Combination; Female; Follow-Up Studies; Health aspects; Humans; Internal Medicine; Losartan; Losartan - therapeutic use; Male; Marfan syndrome; Marfan Syndrome - complications; Pilot Projects; Propranolol - therapeutic use; Treatment Outcome; Young Adult; United States; BB; ARB; BB-L; TGF-β; MFS; AT1; angiotensin II receptor blockade; BB and losartan; transforming growth factor β; AT 1; angiotensin II type 1; β-blockade; Marfan syndrome