Alterations in intestinal microbiota diversity, composition, and function in patients with sarcopenia

• Published in: Scientific reports Vol. 11; no. 1; pp. 4628 - 14
• Main Authors: Kang, Lin, Li, Pengtao, Wang, Danyang, Wang, Taihao, Hao, Dong, Qu, Xuan
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 25.02.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/1647/514/1949; 631/1647/514/2254; 631/326/2565/2134; 692/699/1670/1669; Aging; Biodiversity; Biosynthesis; Gastrointestinal Microbiome; Humanities and Social Sciences; Humans; Inflammation; Intestinal microflora; Intestine; Lipopolysaccharides; Microbiomes; Microbiota; multidisciplinary; Musculoskeletal system; Nutrient transport; Phenylalanine; Protein biosynthesis; Protein transport; RNA, Ribosomal, 16S - genetics; rRNA 16S; Sarcopenia; Sarcopenia - microbiology; Sarcopenia - physiopathology; Science; Science (multidisciplinary); Skeletal muscle; Structure-function relationships; Tryptophan; Tyrosine

16S rRNA sequencing of human fecal samples has been tremendously successful in identifying microbiome changes associated with both aging and disease. A number of studies have described microbial alterations corresponding to physical frailty and nursing home residence among aging individuals. A gut-m...