Wearable and flexible electrochemical sensors for sweat analysis: a review

Flexible wearable sweat sensors allow continuous, real-time, noninvasive detection of sweat analytes, provide insight into human physiology at the molecular level, and have received significant attention for their promising applications in personalized health monitoring. Electrochemical sensors are...

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Published inMicrosystems & nanoengineering Vol. 9; no. 1; pp. 1 - 21
Main Authors Gao, Fupeng, Liu, Chunxiu, Zhang, Lichao, Liu, Tiezhu, Wang, Zheng, Song, Zixuan, Cai, Haoyuan, Fang, Zhen, Chen, Jiamin, Wang, Junbo, Han, Mengdi, Wang, Jun, Lin, Kai, Wang, Ruoyong, Li, Mingxiao, Mei, Qian, Ma, Xibo, Liang, Shuli, Gou, Guangyang, Xue, Ning
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 01.01.2023
Springer Nature B.V
Nature Publishing Group
Subjects
639/301/357
639/638
639/925/350
Biosensors
Chemical sensors
Disease
Energy harvesting
Energy technology
Engineering
Enzymes
Microfluidics
Miniaturization
Personal health
Physiology
Platforms
Power supply
Review
Review Article
Reviews
Sensors
Sweat
Wearable technology
Nanoscale materials
Chemistry
Nanobiotechnology
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Summary:Flexible wearable sweat sensors allow continuous, real-time, noninvasive detection of sweat analytes, provide insight into human physiology at the molecular level, and have received significant attention for their promising applications in personalized health monitoring. Electrochemical sensors are the best choice for wearable sweat sensors due to their high performance, low cost, miniaturization, and wide applicability. Recent developments in soft microfluidics, multiplexed biosensing, energy harvesting devices, and materials have advanced the compatibility of wearable electrochemical sweat-sensing platforms. In this review, we summarize the potential of sweat for medical detection and methods for sweat stimulation and collection. This paper provides an overview of the components of wearable sweat sensors and recent developments in materials and power supply technologies and highlights some typical sensing platforms for different types of analytes. Finally, the paper ends with a discussion of the challenges and a view of the prospective development of this exciting field.
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ISSN:2055-7434
2096-1030
2055-7434
DOI:10.1038/s41378-022-00443-6