HOXBLINC long non-coding RNA activation promotes leukemogenesis in NPM1-mutant acute myeloid leukemia - Zhu, Ganqian; Luo, Huacheng; Feng, Yang; Guryanova, Olga A.; Xu, Jianfeng; Chen, Shi; Lai, Qian; Sharma, Arati; Xu, Bing; Zhao, Zhigang; Feng, Ru; Ni, Hongyu; et al. (Nature communications, 2021)
Keywords: 42; 42/100; 42/109; 42/34; 42/40; 42/89; 45/15; 45/22; 45/77; 45/90; 45/91; 631/136/2441; 631/67/1990/283/1897; 631/67/70; 64; 64/110; 64/60; 692/308/2171; Acute myeloid leukemia; Animals; Carcinogenesis - genetics; Carcinogenesis - metabolism; Carcinogenesis - pathology; Cell Line, Tumor; Cell Proliferation; Chromatin; Gene expression; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Heterografts; Histone-Lysine N-Methyltransferase - genetics; Histone-Lysine N-Methyltransferase - metabolism; Histones - genetics; Histones - metabolism; Homeodomain Proteins - genetics; Homeodomain Proteins - metabolism; Humanities and Social Sciences; Humans; Leukemia; Leukemia, Myeloid, Acute - genetics; Leukemia, Myeloid, Acute - metabolism; Leukemia, Myeloid, Acute - pathology; Leukemogenesis; Loci; Mice; Mice, Transgenic; multidisciplinary; Multigene Family; Mutants; Mutation; Myeloid Ecotropic Viral Integration Site 1 Protein - genetics; Myeloid Ecotropic Viral Integration Site 1 Protein - metabolism; Myeloid leukemia; Myeloid-Lymphoid Leukemia Protein - genetics; Myeloid-Lymphoid Leukemia Protein - metabolism; Myelopoiesis; Myelopoiesis - genetics; Non-coding RNA; Nuclear Proteins - deficiency; Nuclear Proteins - genetics; Nucleoli; Phenotypes; Point mutation; Promoter Regions, Genetic; Ribonucleic acid; RNA; RNA, Long Noncoding - agonists; RNA, Long Noncoding - genetics; RNA, Long Noncoding - metabolism; Science; Science (multidisciplinary); Signal Transduction; Therapeutic targets; Transcription activation; Transcription, Genetic; Transcriptomes; Translocation