The fabrication of an ICA-SF/PLCL nanofibrous membrane by coaxial electrospinning and its effect on bone regeneration in vitro and in vivo

• Published in: Scientific reports Vol. 7; no. 1; pp. 8616 - 12
• Main Authors: Yin, Lihua, Wang, Kaijuan, Lv, Xiaoqin, Sun, Rui, Yang, Shaohua, Yang, Yujie, Liu, Yanyun, Liu, Jiatao, Zhou, Jing, Yu, Zhanhai
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 17.08.2017; Nature Publishing Group; Nature Portfolio
• Subjects: 13/106; 13/107; 14/28; 64; 692/308; 692/700; 82/1; Biocompatibility; Bone growth; Defects; Fabrication; Flavonoids; Humanities and Social Sciences; Membranes; multidisciplinary; Osteogenesis; Regeneration; Science; Science (multidisciplinary)

GBR is currently accepted as one of the most effective approaches for bone defect regeneration relating to dental implant. Icariin is the main active ingredient in the extraction of total flavonoids from the Chinese traditional herb Epimediumbrevicornum Maxim. In this study, ICA was successfully inc...