Wireless, battery-free, and fully implantable electrical neurostimulation in freely moving rodents

• Published in: Microsystems & nanoengineering Vol. 7; no. 1; pp. 62 - 12
• Main Authors: Burton, Alex, Won, Sang Min, Sohrabi, Arian Kolahi, Stuart, Tucker, Amirhossein, Amir, Kim, Jong Uk, Park, Yoonseok, Gabros, Andrew, Rogers, John A., Vitale, Flavia, Richardson, Andrew G., Gutruf, Philipp
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 13.08.2021; Springer Nature B.V; Nature Publishing Group
• Subjects: 639/166/987; 639/925/350/1057; Animal models; Antennas; Chronic pain; Deep brain stimulation; Electrodes; Engineering; Forebrain; Head movement; In vivo methods and tests; Medial forebrain bundle; Movement disorders; Neural prostheses; Neurodegenerative diseases; Parkinson's disease; Power; Rodents; Stimulation; Stimulators; Electrical and electronic engineering; Bionanoelectronics

Implantable deep brain stimulation (DBS) systems are utilized for clinical treatment of diseases such as Parkinson’s disease and chronic pain. However, long-term efficacy of DBS is limited, and chronic neuroplastic changes and associated therapeutic mechanisms are not well understood. Fundamental an...