Association of NF-E2 Related Factor 2 (Nrf2) and inflammatory cytokines in recent onset Type 2 Diabetes Mellitus

• Published in: Scientific reports Vol. 8; no. 1; pp. 5126 - 10
• Main Authors: Sireesh, Dornadula, Dhamodharan, Umapathy, Ezhilarasi, Krishnamoorthy, Vijay, Viswanathan, Ramkumar, Kunka Mohanram
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 23.03.2018; Nature Publishing Group
• Subjects: 38/77; 631/45/127/1213; 692/163/2743/137/773; 96/21; Blood glucose; Cytokines; Diabetes; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Glucose; Humanities and Social Sciences; Inflammation; Insulin; Insulin secretion; Leukocytes (mononuclear); Lymphocytes T; multidisciplinary; NRF2 protein; Oxidative stress; Pancreas; Peripheral blood mononuclear cells; Regression analysis; Remission; Science; Science (multidisciplinary)

We investigated the association of redox regulator Nuclear factor erythroid 2-related factor 2 (Nrf2) and inflammatory cytokines as well as clinical remission in patients with recent onset type 2 diabetes (DM). Blood was collected from 180 DM patients (105 males/75 females) and 150 control subjects...