Monitoring longitudinal disease progression in a novel murine Kit tumor model using high-field MRI

• Published in: Scientific reports Vol. 12; no. 1; pp. 14608 - 14
• Main Authors: Kraiger, Markus, Klein-Rodewald, Tanja, Rathkolb, Birgit, Calzada-Wack, Julia, Sanz-Moreno, Adrián, Fuchs, Helmut, Wolf, Eckhard, Gailus-Durner, Valérie, de Angelis, Martin Hrabě
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 26.08.2022; Nature Publishing Group; Nature Portfolio
• Subjects: 631/67/1347; 631/67/1504; 631/67/2321; 631/67/70; Animal models; Animals; Bone marrow; Breast cancer; Cecum; Disease Progression; Ethyl nitrosourea; Female; Genotypes; Hemangioma; Humanities and Social Sciences; Leukemia; Magnetic Resonance Imaging; Male; Mammary Neoplasms, Animal; Mice; Mice, Inbred C3H; multidisciplinary; Mutants; Science; Science (multidisciplinary); Spleen; Therapeutic applications; Tumors

Animal models are an indispensable platform used in various research disciplines, enabling, for example, studies of basic biological mechanisms, pathological processes and new therapeutic interventions. In this study, we applied magnetic resonance imaging (MRI) to characterize the clinical picture o...