Crosstalk between G-quadruplex and ROS

• Published in: Cell death & disease Vol. 14; no. 1; pp. 37 - 16
• Main Authors: Wu, Songjiang, Jiang, Ling, Lei, Li, Fu, Chuhan, Huang, Jinhua, Hu, Yibo, Dong, Yumeng, Chen, Jing, Zeng, Qinghai
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 18.01.2023; Springer Nature B.V; Nature Publishing Group
• Subjects: 631/337/100/101; 631/80/509; Aging; Antibodies; Biochemistry; Biomedical and Life Sciences; Cations; Cell Biology; Cell Culture; DNA - metabolism; DNA damage; Epigenesis, Genetic; Epigenetics; G-Quadruplexes; Gene regulation; Immunology; Life Sciences; Neurodegeneration; Neurodegenerative diseases; Nucleic acids; Reactive oxygen species; Reactive Oxygen Species - metabolism; Redox potential; Regulatory sequences; Regulatory Sequences, Nucleic Acid; Review; Review Article; Telomeres; Transcription factors; Translation

The excessive production of reactive oxygen species (ROS) can lead to single nucleic acid base damage, DNA strand breakage, inter- and intra-strand cross-linking of nucleic acids, and protein-DNA cross-linking involved in the pathogenesis of cancer, neurodegenerative diseases, and aging. G-quadruple...