Survival improvement for patients with metastatic colorectal cancer over twenty years

• Published in: NPJ precision oncology Vol. 7; no. 1; pp. 16 - 9
• Main Authors: Zeineddine, Fadl A., Zeineddine, Mohammad A., Yousef, Abdelrahman, Gu, Yue, Chowdhury, Saikat, Dasari, Arvind, Huey, Ryan W., Johnson, Benny, Kee, Bryan, Lee, Michael S., Morelli, Maria Pia, Morris, Van K., Overman, Michael J., Parseghian, Christine, Raghav, Kanwal, Willis, Jason, Wolff, Robert A., Kawaguchi, Yoshikuni, Vauthey, Jean-Nicolas, Sun, Ryan, Kopetz, Scott, Shen, John Paul
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 13.02.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 692/4028/67/1059/99; 692/4028/67/1504/1885; 692/53/2422; 692/699/1503/1504/1885; Antiviral drugs; Cancer Research; Chemotherapy; Colorectal cancer; Gene Therapy; Human Genetics; Immunotherapy; Inhibitor drugs; Internal Medicine; Medicine; Medicine & Public Health; Metastasis; Oncology; Targeted cancer therapy

Over the past two decades of successive clinical trials in metastatic colorectal cancer (CRC), the median overall survival of both control and experimental arms has steadily improved. However, the incremental change in survival for metastatic CRC patients not treated on trial has not yet been quanti...