SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules - Zheng, Yi; Deng, Jian; Han, Lulu; Zhuang, Meng-Wei; Xu, Yanwen; Zhang, Jing; Nan, Mei-Ling; Xiao, Yang; Zhan, Peng; Liu, Xinyong; Gao, Chengjiang; Wang, Pei-Hui (Signal transduction and targeted therapy, 2022)
Keywords: 631/250/262; 692/699/255; Animals; Antiviral drugs; Cancer Research; Cell Biology; Chlorocebus aethiops; Cofactors; Coronavirus 3C Proteases - genetics; Coronavirus 3C Proteases - immunology; Coronavirus Nucleocapsid Proteins - genetics; Coronavirus Nucleocapsid Proteins - immunology; Coronaviruses; COVID-19; DEAD Box Protein 58 - genetics; DEAD Box Protein 58 - immunology; DNA Helicases - genetics; DNA Helicases - immunology; Double-stranded RNA; Ectopic expression; Gene Expression Regulation; HEK293 Cells; HeLa Cells; Humans; Immune Evasion; Infections; Innate immunity; Interferon; Interferon regulatory factor 3; Internal Medicine; Medicine; Medicine & Public Health; N protein; Oncology; Pathology; Phosphoproteins - genetics; Phosphoproteins - immunology; Phosphorylation; Poly I-C - pharmacology; Poly-ADP-Ribose Binding Proteins - genetics; Poly-ADP-Ribose Binding Proteins - immunology; Polyinosinic:polycytidylic acid; Protein Binding; Proteins; Receptors, Immunologic - genetics; Receptors, Immunologic - immunology; RNA Helicases - genetics; RNA Helicases - immunology; RNA Recognition Motif Proteins - genetics; RNA Recognition Motif Proteins - immunology; RNA, Double-Stranded - genetics; RNA, Double-Stranded - immunology; RNA-Binding Proteins - genetics; RNA-Binding Proteins - immunology; SARS-CoV-2 - genetics; SARS-CoV-2 - immunology; SARS-CoV-2 - pathogenicity; Sendai virus - genetics; Sendai virus - immunology; Severe acute respiratory syndrome coronavirus 2; Signal Transduction; Stomatitis; Stress Granules - drug effects; Stress Granules - genetics; Stress Granules - immunology; Stress Granules - virology; Transfection; Vero Cells; Vesiculovirus - genetics; Vesiculovirus - immunology