A pilot study shows the positive effects of continuous airway pressure for treating hypernasal speech in children with infantile-onset Pompe disease

• Published in: Scientific reports Vol. 11; no. 1; pp. 18826 - 8
• Main Authors: Zeng, Yin-Ting, Liu, Wen-Yu, Torng, Pao-Chuan, Hwu, Wuh-Liang, Lee, Ni-Chung, Lin, Chun-Yi, Chien, Yin-Hsiu
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 22.09.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/136/368; 692/1807; 692/420; 692/617; 692/699; 692/699/3020; 692/699/375; 692/700; 692/700/228/2050/1510; 692/700/228/491; Articulation Disorders - etiology; Articulation Disorders - therapy; Child; Child, Preschool; Children; Continuous positive airway pressure; Continuous Positive Airway Pressure - methods; Cross-Over Studies; Enzymes; Experimental design; Female; Glycogen Storage Disease Type II - complications; Glycogen Storage Disease Type II - therapy; Humanities and Social Sciences; Humans; Male; Medical research; multidisciplinary; Patients; Pilot Projects; Respiratory tract; Science; Science (multidisciplinary); Speech; Speech disorders; Speech Intelligibility; Speech Therapy; Training

Children with infantile-onset Pompe disease (IOPD) demonstrate hypernasality. This study aimed to evaluate whether continuous positive airway pressure (CPAP) training may reduce hypernasality in children with IOPD. Five children with IOPD were enrolled in a single-subject experimental design of type...